SynthesisNeuroImage2020
Anchoring the human olfactory system within a functional gradient.
Synthesis in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Olfactory Bulb Volume Reflects Olfactory Dysfunction and Network Organization: Insights From the Population-Based Rhineland Study.International forum of allergy & rhinology · 2026Article
- The genetic architecture of cortical similarity networks.Nature communications · 2026Article
- Integrating olfactory assessments in consciousness disorders: methodologies and therapeutic potential.Frontiers in neurology · 2026Review
- From hidden springs to endless oceans: exploring the complementary roles of the amygdala and hippocampus in phenomenal experience.Neuroscience of consciousness · 2026Article
- COVID-19 infection and longitudinal changes in olfactory-related brain structures in children: analysis of ABCD study data.European journal of pediatrics · 2025Observational
- Mapping the Olfactory Brain: A Systematic Review of Structural and Functional Magnetic Resonance Imaging Changes Following COVID-19 Smell Loss.Brain sciences · 2025Review
- The human olfactory amygdala: Anatomical connections between the olfactory bulb and amygdala subregions.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Gait dynamics and brain function abnormalities in Parkinson's disease with freezing of gait: a clinical study using resting-state fMRI and wearable devices.Frontiers in neuroscience · 2025Article
- Relating sex-bias in human cortical and hippocampal microstructure to sex hormones.Nature communications · 2024Article
- Omnipresence of the sensorimotor-association axis topography in the human connectome.NeuroImage · 2023Article
- Is it left or is it right? A classification approach for investigating hemispheric differences in low and high dimensionality.Brain structure & function · 2022Article
- Imaging evolution of the primate brain: the next frontier?NeuroImage · 2021Review
- Mapping the principal gradient onto the corpus callosum.NeuroImage · 2020Article
- Olfactory Testing With Focus on Odor Identification for Early Detection of Alzheimer's Disease in Mild Cognitive Impairment.American journal of Alzheimer's disease and other dementiasReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Margulies et al. (2016) demonstrated the existence of at least five independent functional connectivity gradients in the human brain. However, it is unclear how these functional gradients might link to anatomy. The dual origin theory proposes that differences in cortical cytoarchitecture originate from two trends of progressive differentiation between the different layers of the cortex, referred to as the hippocampocentric and olfactocentric systems. When conceptualising the functional connectivity gradients within the evolutionary framework of the Dual Origin theory, the first gradient likely represents the hippocampocentric system anatomically. Here we expand on this concept and demonstrate that the fifth gradient likely links to the olfactocentric system. We describe the anatomy of the latter as well as the evidence to support this hypothesis. Together, the first and fifth gradients might help to model the Dual Origin theory of the human brain and inform brain models and pathologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.