Evidence map›Paper›PMID 32325011›Full record

ArticleJornal de pediatria

Epidemiological evaluation and survival of children with acute myeloid leukemia.

Rahuany Velleda de Morais, Meriene Viquetti de Souza, Klerize Anecely de Souza Silva, Pablo Santiago, Marcelo Cunha Lorenzoni, Cecília Fernandes Lorea, Cláudio Galvão de Castro Junior, Adriano Nori Rodrigues Taniguchi, Fernanda Fetter Scherer, Mariana Bohns Michalowski and 1 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  11. Mutational Landscape ofFrontiers in pediatrics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Rahuany Velleda de MoraisUniversidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil.
Meriene Viquetti de SouzaUniversidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Porto Alegre, RS, Brazil; Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Klerize Anecely de Souza SilvaUniversidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Porto Alegre, RS, Brazil; Hospital da Criança Conceição, Porto Alegre, RS, Brazil.
Pablo SantiagoHospital São Vicente de Paulo, Passo Fundo, RS, Brazil.
Marcelo Cunha LorenzoniHospital São Vicente de Paulo, Passo Fundo, RS, Brazil.
Cecília Fernandes LoreaHospital Escola, Universidade Federal de Pelotas (UFPEL), Pelotas, RS, Brazil.
Cláudio Galvão de Castro JuniorHospital da Criança Santo Antônio, Porto Alegre, RS, Brazil.
Adriano Nori Rodrigues TaniguchiHospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Fernanda Fetter SchererHospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Mariana Bohns MichalowskiHospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Liane Esteves DaudtUniversidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Porto Alegre, RS, Brazil; Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil. Electronic address: ldaudt@hcpa.edu.br.
Hospital de Clínicas de Porto Alegre · BRUniversidade Federal do Rio Grande do Sul · BRHospital São Vicente de Paulo · BRHospital Nossa Senhora da Conceição · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BRUniversidade Federal de Pelotas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to describe the epidemiological characteristics and survival rates of children with acute myeloid leukemia treated in hospitals in southern Brazil and compare them with international data.

methodsA multicenter cohort study was conducted with retrospective data collection of all new patients with acute myeloid leukemia under 18 treated at five referral centers in pediatric hematology-oncology in southern Brazil between January 2005 and December 2015.

resultsOf the 149 patients with acute myeloid leukemia, 63.0% (n=94) were male. The median age at diagnosis was 10.5 years (range 0-18 years) and 40.3% (n=60) had a white blood cell count below 50,000/mm

conclusionsThese results show a higher prevalence of the Franco-American-British M3 subtype than that reported in the international literature, as well as a decreased OS compared with that of developed countries. Further multicenter Brazilian studies with a larger sample size are encouraged to better understand the characteristics of acute myeloid leukemia, and to improve the treatment and prognosis in this population.

Indexed as

Leukemia, Myeloid, AcuteAdolescentBrazilChildChild, PreschoolCohort StudiesHumansInfantInfant, NewbornMalePrognosisRetrospective StudiesAcute myeloid leukemiaChildhoodEpidemiology

Identifiers

PMID32325011
PMCPMC9432146
OpenAlexW3019661398

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.