Evidence map›Paper›PMID 32324980›Full record

ArticleChronic obstructive pulmonary diseases (Miami, Fla.)2020

The Association of Multiparity with Lung Function and Chronic Obstructive Pulmonary Disease-Related Phenotypes.

Matthew Moll, Elizabeth A Regan, John E Hokanson, Sharon M Lutz, Edwin K Silverman, James D Crapo, Barry J Make, Dawn L DeMeo

Open access · diamondAbstract read
In one paragraph

Article in Chronic obstructive pulmonary diseases (Miami, Fla.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. An Examination of Sex Differences and Cigarette Smoking as Predictors of COPD Prevalence and Incidence in Older US Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
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  7. Review
  8. Sex Hormones and Lung Inflammation.Advances in experimental medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Matthew MollChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Elizabeth A ReganDivision of Rheumatology, National Jewish Health, Denver, Colorado.
John E HokansonDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora.
Sharon M LutzPRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts.
Edwin K SilvermanChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
James D CrapoDivision of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, Colorado.
Barry J MakeDivision of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, Colorado.
Dawn L DeMeoChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
University of Colorado Denver · USBrigham and Women's Hospital · USColorado School of Public Health · USHarvard University · US

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Respiratory Computational Discovery CoreP01HL114501 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI HERSH, CRAIG P · 2013 to 2025
$24.9M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
Systems Biology of Airway DiseaseP01HL132825 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMEO, DAWN L · 2016 to 2020
$12.6M
COPD Susceptibility, Heterogeneity, and Progression: Proteomics and GeneticsR01HL133135 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MORITZ, ROBERT L, SILVERMAN, EDWIN K · 2017 to 2025
$7.2M
Genetic and Functional Dissection of a Cluster of COPD GWAS Signals on Chromosome 4qR01HL147148 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., SILVERMAN, EDWIN K · 2019 to 2022
$3.5M
Identifying functional variants in COPD GWAS lociR01HL137927 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., SILVERMAN, EDWIN K · 2017 to 2020
$3.5M
Common Genetic Pathways Underlying CVD and COPDK01HL125858 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI LUTZ, SHARON MARIE · 2015 to 2019
$721k
COPD Foundation Industry Advisory BoardNHLBI NIH HHS K01 HL125858NHLBI NIH HHS P01 HL114501NHLBI NIH HHS P01 HL132825NHLBI NIH HHS R01 HL133135NHLBI NIH HHS R01 HL137927NHLBI NIH HHS R01 HL147148NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897
6 · The paper itself

Abstract

backgroundApparent increased female susceptibility to chronic obstructive pulmonary disease (COPD) suggests sex hormones modulate disease pathogenesis. Little is known about associations between multiparity and lung function in smokers. RESEARCH QUESTION: We hypothesized that multiparity is associated with lung function and measures of emphysema and airway disease. STUDY DESIGN AND

methodsUtilizing female participants from the 5-year follow up of the COPD Genetic Epidemiology (COPDGene

resultsWe included 1820 participants from COPDGene

interpretationMultiparity was associated with lower FEV

Indexed as

chronic obstructive pulmonary diseasecopdfemalehormonesmultiparityphenotypespregnancy

Identifiers

PMID32324980
PMCPMC7454017
OpenAlexW3019240304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.