ArticleJournal of diabetes investigation2020
Excessive gestational weight gain in the first and second trimester is a risk factor for gestational diabetes mellitus among women pregnant with singletons: A repeated measures analysis.
Article in Journal of diabetes investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- The impact of health coaching on the prevention of gestational diabetes in overweight/obese pregnant women: a quasi-experimental study.BMC women's health · 2023Trial
- Early pregnancy body mass index outweighs gestational weight gain in predicting gestational diabetes mellitus: A single-center experience from Türkiye.Qatar medical journal · 2026Article
- Glucose metabolism, lipid metabolism, and body composition of pregnant women personalized nutritional management based on pre-pregnancy BMI and percent body fat.Frontiers in nutrition · 2026Article
- Participant characteristics in the effectiveness of lifestyle interventions to optimize gestational weight gain: a systematic review and meta-analysis.Communications medicine · 2025Article
- Establishment of a risk prediction model for large-for-gestational-age infants among Chinese women with gestational diabetes mellitus.Scientific reports · 2025Article
- Fecal microbiota transplantation from gestational diabetes mellitus patients induces glucose intolerance and subclinical inflammation in mice.Frontiers in microbiology · 2025Article
- Seeking the optimal gestational weight gain according to the pre-pregnancy body mass index: a cross-sectional study from Shanghai, China.European journal of clinical nutrition · 2025Article
- Gestational weight gain and body mass index in Asian Indian women: Impact of timing and amount on fetomaternal outcomes.Journal of family medicine and primary care · 2024Article
- Twin Pregnancy Complicated by Gestational Diabetes Mellitus: Maternal and Neonatal Outcomes.Journal of the Endocrine Society · 2024Article
- Weight progression and adherence to weight gain target in women with vs. without gestational diabetes: a retrospective cohort study.BMC pregnancy and childbirth · 2023Article
- An mHealth Intervention to Reduce Gestational Obesity (mami-educ): Protocol for a Randomized Controlled Trial.JMIR research protocols · 2023Article
- Effect of excessive gestational weight gain before and after 28 weeks on trial of labor after cesarean stratified by pre-pregnancy body mass index: a retrospective cohort study.Frontiers in medicine · 2023Article
- Development and Validation of Risk Prediction Models for Gestational Diabetes Mellitus Using Four Different Methods.Metabolites · 2022Article
- Gestational Diabetes Mellitus as an Effect Modifier of the Association of Gestational Weight Gain with Perinatal Outcomes: A Prospective Cohort Study in China.International journal of environmental research and public health · 2022Article
- Epigenetic Links between Microbiota and Gestational Diabetes.International journal of molecular sciences · 2022Review
- The association between weight gain at different stages of pregnancy and risk of gestational diabetes mellitus.Journal of diabetes investigation · 2022Article
- The Influence of HbA1c and Gestational Weight Gain on Pregnancy Outcomes in Pregnant Women With Gestational Diabetes Mellitus.Frontiers in medicine · 2022Article
- Gestational Diabetes Mellitus: A Harbinger of the Vicious Cycle of Diabetes.International journal of molecular sciences · 2020Review
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
AIMS/
introductionTo evaluate gestational weight gain (GWG) in the first and second trimester as a risk factor for gestational diabetes mellitus (GDM) among women pregnant with singletons. MATERIALS AND
methodsThis was a cohort study of women with singleton pregnancies who delivered between 1 January 2013 and 31 October 2014 in a Chinese hospital. We collected data from medical records from the first antenatal visit to delivery. All pregnant women were subjected to an oral glucose tolerance test for diagnosis of GDM during the second trimester. GWG in the first and second trimester was calculated by subtracting the prepregnancy weight from weight within 4 weeks of the oral glucose tolerance test. We categorized GWG into insufficient, appropriate and excessive according to the Institute of Medicine guidelines and population quantiles. Univariable and multivariable analyses were used to determine the association between GWG and GDM risk.
resultsOf 10,422 pregnant women, we identified 8,356 eligible women with 1,622 (19.4%) diagnosed with GDM. Univariable analysis showed that GWG that exceeded the Institute of Medicine recommendation might be associated with risk of GDM (P < 0.05), but this association was not observed by multivariable analysis (adjusted odds ratio 1.07, [95% confidence interval 0.94-1.21]). Univariable and multivariable analyses both showed that GWG exceeding the 90th and 95th quantiles of included women, respectively, were at increased risk for GDM (adjusted odds ratio >P
conclusionsExcessive GWG in the first and second trimester might be a risk factor for GDM, which highlights the importance of appropriate weight gain during pregnancy.
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