SynthesisPloS one2020
The neglected role of Enterobius vermicularis in appendicitis: A systematic review and meta-analysis.
Synthesis in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
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The trial behind it
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Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Worldwide prevalence of protozoans and helminths among disabled people: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Prevalence of intestinal parasitic infections in patients with diabetes: a systematic review and meta-analysis.International health · 2024Pooled it
- Parasites in surgically removed appendices as a neglected public health concern: a systematic review and meta-analysis.Pathogens and global health · 2022Pooled it
- Global molecular epidemiology of microsporidia in pigs and wild boars with emphasis on Enterocytozoon bieneusi: A systematic review and meta-analysis.Veterinary medicine and science · 2022Pooled it
- Enterobius vermicularis as a Mimic of Acute Appendicitis: A Case Report and Updated Systematic Review.Cureus · 2026Article
- Article
- Fifteen-minute consultation: Threadworm in children.Archives of disease in childhood. Education and practice edition · 2026Article
- Pinworm (Frontiers in public health · 2026Review
- Enterobius vermicularis as a cause of acute appendicitis: a case report.Frontiers in medicine · 2026Article
- Article
- Estimating the Prevalence of Parasitic Infections in Migrant Workers in The Middle East: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2025Review
- Article
- Incidentally-detected nonspecific and unusual histopathological findings in childhood appendectomy specimens: a retrospective analysis of 2633 cases.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Article
- Article
- Parasitic appendicitis, what do we know?-a literature review.Translational gastroenterology and hepatology · 2025Review
- Enterobius vermicularis (pinworm) infestation mimicking acute appendicitis in two children from Palestine: a case report.Journal of medical case reports · 2024Article
- Humans seropositive for Trypanosoma cruzi co-infected with intestinal helminths have higher infectiousness, parasitaemia and Th2-type response in the Argentine Chaco.Parasites & vectors · 2024Article
- Management and Incidence ofJournal of clinical medicine · 2024Article
- Intestinal Helminths Infections as Infrequent Cause of Emergency Abdominal Surgery: A Retrospective Study in a University Hospital over 20 Years.Acta parasitologica · 2024Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the main cause of appendicitis is unclear, infection with Enterobius vermicularis is suggested as a neglected risk factor. Since, there is no comprehensive analysis to estimate the prevalence of E. vermicularis in appendicitis; therefore, we conducted a global-scale systematic review and meta-analysis study to estimate the prevalence of E. vermicularis infection in appendicitis cases. PubMed, Scopus, Web of Science and Google Scholar databases were systematically searched for relevant studies published until 15 August 2019. Pooled prevalence of E. vermicularis infection was estimated using the random effects model. Data were classified based on the continents and countries. Moreover, subgroup analyses regarding the gender, the human development index (HDI), and income level of countries were also performed. Fifty-nine studies involving 103195 appendix tissue samples belonging to the individuals of appendicitis were included. The pooled prevalence of E. vermicularis infection was (4%, 95%CI, 2-6%), with the highest prevalence (8%, 95% CI: 0-36%) and lowest prevalence (2%, 95% CI: 1-4%) in Africa and Americas continents, respectively. With respect to countries, the lowest and highest prevalence rates were reported from Venezuela (<1%, 95% CI: 0-1%) and Nigeria (33%, 95% CI: 17-52%), respectively. Indeed, a higher prevalence was observed in females, as well as in countries with lower levels of income and HDI. Our findings indicate the relatively high burden of E. vermicularis infection in appendicitis cases. However, our findings suggest the great need for more epidemiological studies to depth understand overlaps between E. vermicularis infection and appendicitis in countries with lower HDI and income levels.
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