SynthesisPloS one2020
Gestational weight gain and its effect on birth outcomes in sub-Saharan Africa: Systematic review and meta-analysis.
Synthesis in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 5 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- The effects of antenatal interventions on gestational weight gain in low and middle-income countries: a systematic review.BMJ global health · 2026Pooled it
- Prevalence, risk factors and outcomes of macrosomia in Africa: a systematic review and meta-analysis.BMJ open · 2026Pooled it
- Suboptimal gestational weight gain and neonatal outcomes in low and middle income countries: individual participant data meta-analysis.BMJ (Clinical research ed.) · 2023Pooled it
- Effects of prenatal nutritional supplements on gestational weight gain in low- and middle-income countries: a meta-analysis of individual participant data.The American journal of clinical nutrition · 2022Pooled it
- Gestational weight gain and its effect on birth outcomes in sub-Saharan Africa: Systematic review and meta-analysis.PloS one · 2020Pooled it
- Effect of nutrition education integrating the health belief model and theory of planned behavior during pregnancy on gestational weight gain and birth weight in Southeast Ethiopia using complex analyses.BMC pregnancy and childbirth · 2025Trial
- Fortified Balanced Energy-Protein Supplementation, Maternal Anemia, and Gestational Weight Gain: A Randomized Controlled Efficacy Trial among Pregnant Women in Rural Burkina Faso.The Journal of nutrition · 2022Trial
- Gestational weight gain during the second and third trimesters and adverse pregnancy outcomes, results from a prospective pregnancy cohort in urban Tanzania.Reproductive health · 2022Trial
- Multivitamin Supplementation Is Associated with Greater Adequacy of Gestational Weight Gain among Pregnant Women in Tanzania.The Journal of nutrition · 2022Trial
- Relationship Between Pre-Pregnancy Body Mass Index, Gestational Weight Gain, and Perinatal Outcomes Among Women Delivering at a General Hospital, Nakhon Si Thammarat Province.International journal of environmental research and public health · 2026Article
- Magnitude and determinants of gestational weight gain in Ethiopia: a systematic review and meta-analysis.Maternal health, neonatology and perinatology · 2026Review
- Knowledge, attitude, and practices on gestational weight gain among pregnant women, partners, female household members, and healthcare providers: a mixed-method study in Tanzania.BMC pregnancy and childbirth · 2026Article
- Inadequate Gestational Weight Gain and Associated Factors Among Pregnant Women in Gamo Zone Public Hospitals, South Ethiopia: A Facility-Based Cross-Sectional Study.Journal of pregnancy · 2026Article
- Prenatal multiple micronutrient supplementation is associated with improved maternal gestational weight gain: A prospective longitudinal study in Parepare, Indonesia.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Association between gestational weight gain and adverse pregnancy outcomes: a systematic review and meta-analysis.Frontiers in global women's health · 2026Review
- The Impact of Excessive Gestational Weight Gain on Adverse Perinatal Outcomes: A Systematic Review.Journal of clinical medicine · 2025Review
- Gestational weight gain and its determinants among pregnant women attending antenatal care at West Shawa Hospitals, Oromia, Ethiopia.PloS one · 2025Article
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Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAn increased metabolic demand during pregnancy is fulfilled by gaining sufficient gestational weight. Women who gain inadequate-weight are at a high-risk of premature birth or having a baby with low-birth weight. However, women who gain excessive-weight are at a high-risk of having a baby with macrosomia. The aim of this review was to determine the distribution of gestational weight gain and its association with birth-outcomes in Sub-Saharan Africa.
methodsFor this systematic review and meta-analysis, we performed a literature search using PubMed, Medline, Embase, Scopus, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases. We searched grey-literature from Google and Google Scholar, and region-specific journals from the African Journals Online (AJOL) database. We critically appraised the included studies using the Effective Public Health Practice Project Quality Assessment Tool for Quantitative Studies. Two independent reviewers evaluated the quality of the studies and extracted the data. We calculated pooled relative-risks (RR) with 95% confidence intervals.
resultsOf 1450 retrieved studies, 26 met the inclusion criteria. Sixteen studies classified gestational weight gain according to the United States Institute of Medicine recommendations. The percentage adequate amount of gestational weight ranged from 3% to 62%. The percentage of inadequate weight was >50% among nine studies. Among underweight women, the percentage of women who gained inadequate gestational weight ranged from 67% to 98%. Only two studies were included in the meta-analyses to evaluate the association of gestational weight gain with pre-eclampsia and macrosomia. No difference was observed among women who gained inadequate and adequate gestational weight regarding experiencing pre-eclampsia (RR, 0.71; 95% CI: 0.22, 2.28, P = 0.57). Excessive gestational weight gain was not significantly associated with macrosomia compared to adequate weight gain (RR, 0.68; 95% CI: 0.38, 1.22, P = 0.20).
conclusionA substantial proportion of sub-Saharan African women gain inadequate gestational weight particularly high among underweight women. Future interventions would need to design effective pre-pregnancy weight management strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.