Evidence map›Paper›PMID 32324307›Full record

ArticleClinical cardiology2020

Rationale and design of a smartphone-enabled, home-based exercise program in patients with symptomatic peripheral arterial disease: The smart step randomized trial.

Arash Harzand, Alexander A Vakili, Alaaeddin Alrohaibani, Smah M Abdelhamid, Neil F Gordon, John Thiel, Jaime Benarroch-Gampel, Victoria J Teodorescu, Keri Minton, Nanette K Wenger and 2 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Arash HarzandDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-9192-9338
Alexander A VakiliDepartment of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Alaaeddin AlrohaibaniDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Smah M AbdelhamidDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Neil F GordonINTERVENT International, Savannah, Georgia, USA.
John ThielINTERVENT International, Savannah, Georgia, USA.
Jaime Benarroch-GampelDivision of Vascular Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Victoria J TeodorescuDivision of Vascular Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Keri MintonGrady Memorial Hospital, Atlanta, Georgia, USA.
Nanette K WengerDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0003-0990-6151
Ravi R RajaniDivision of Vascular Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Amit J ShahDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Funding

Emory University
6 · The paper itself

Abstract

backgroundSupervised exercise therapy (SET) is recommended in patients with symptomatic peripheral arterial disease (PAD) as first-line therapy, although patient adoption remains low. Home-based exercise therapy (HBET) delivered through smartphones may expand access. The feasibility of such programs, especially in low-resource settings, remains unknown.

methodsSmart Step is a pilot randomized trial of smartphone-enabled HBET vs walking advice in patients with symptomatic PAD in an inner-city hospital. Participants receive a smartphone app with daily exercise reminders and educational content. A trained coach performs weekly phone-based coaching sessions. All participants receive a Fitbit Charge HR 2 to measure physical activity. The primary outcome changes in 6-minute walking test (6MWT) distance at 12 weeks over baseline. Secondary outcomes are the degree of engagement with the smartphone app and changes in health behaviors and quality of life scores after 12 weeks and 1 year.

resultsA total of 15 patients are randomized as of December 15, 2019 with a mean (SD) age of 66.1 (5.8) years. The majority are female (60%) and black (87%). At baseline, the mean (SD) ABI and 6MWT were 0.86 (0.29) and 363.5 m, respectively. Enrollment is expected to continue until December 2020 to achieve a target size of 50 participants.

conclusionsThe potential significance of this trial will be to provide preliminary evidence of a home-based, "mobile-first" approach for delivering a structured exercise rehabilitation program. Smartphone-enabled HBET can be potentially more accessible than center-based programs, and if proven effective, may have a potential widespread public health benefit.

Indexed as

Quality of LifeSmartphoneAgedExerciseExercise TherapyFemaleFollow-Up StudiesHumansMalePeripheral Arterial DiseasePilot ProjectsProspective StudiesRandomized Controlled Trials as TopicTelemedicine

Identifiers

PMID32324307
PMCPMC7298994

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.