Evidence map›Paper›PMID 32323890›Full record

ArticlePediatric blood & cancer2020

Higher plasma asparaginase activity after intramuscular than intravenous Erwinia asparaginase.

John C Panetta, Yiwei Liu, Hope D Swanson, Seth E Karol, Ching-Hon Pui, Hiroto Inaba, Sima Jeha, Mary V Relling

Open access · greenAbstract readComparative Study
In one paragraph

Article in Pediatric blood & cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

John C PanettaDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0003-1308-7208
Yiwei LiuDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
Hope D SwansonDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
Seth E KarolDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0001-8113-8180
Ching-Hon PuiDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0003-0303-5658
Hiroto InabaDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0003-0605-7342
Sima JehaDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Mary V RellingDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0002-3720-9591
St. Jude Children's Research Hospital · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Glucocorticoids in Lymphoblastic LeukemiaR01CA142665 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI RELLING, MARY V · 2010 to 2020
$4.6M
NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA142665NIH HHS CA 142665NIH HHS CA 21765
6 · The paper itself

Abstract

It is unclear if dosing intervals for Erwinase can be extended with intramuscular (i.m.) versus intravenous (i.v.) dosing. Children with acute lymphoblastic leukemia received Erwinase at 30 000-42 000 IU/m

Indexed as

Antineoplastic AgentsAsparaginaseChildErwiniaFollow-Up StudiesHumansInjections, IntramuscularInjections, IntravenousPrecursor Cell Lymphoblastic Leukemia-LymphomaAntineoplastic AgentsAsparaginaseacute lymphoblastic leukemiaasparaginaseErwinaseintramuscularintravenouspharmacokinetics

Identifiers

PMID32323890
PMCPMC7253324
OpenAlexW3019129793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.