ArticleThe New phytologist2020
The root-invading pathogen Fusarium oxysporum targets pattern-triggered immunity using both cytoplasmic and apoplastic effectors.
Article in The New phytologist, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Host genetic variation is associated with root-associated microbiome assembly and resistance to Fusarium oxysporum in tobacco.Plant physiology · 2026Article
- A tomato MIK2-clade receptor is involved in the perception of a Fusarium-derived elicitor.The New phytologist · 2026Article
- Heterologous Systems in the Functional Characterization of Proteins from Phytopathogenic Fungi: A Systematic Review.Molecular biotechnology · 2026Article
- Involvement ofJournal of fungi (Basel, Switzerland) · 2026Article
- Powdery Scab of Potato: An Evaluation of Current Molecular Resources.Environmental microbiology reports · 2026Review
- Horizontal Chromosome Transfer between Pathogenic and Non-pathogenic Fusarium oxysporum Strains Isolated from Cabbage.Microbes and environments · 2026Article
- Gap-free comparative genomics uncover virulence factors for Fusarium wilt of watermelons.PLoS pathogens · 2025Article
- Bacterial extracellular biomolecules-derived multimodal manganese nanoparticles control watermelon Fusarium wilt by dysregulating fusaric acid biosynthesis pathway and precise tuning of rhizosphere metabolome.Journal of nanobiotechnology · 2025Article
- Resolving spatially distinct phytohormone response zones in Arabidopsis thaliana roots colonized by Fusarium oxysporum.Journal of experimental botany · 2025Article
- Involvement of the SIX10 Gene in the Pathogenicity ofInternational journal of molecular sciences · 2025Article
- Effectors of plants pathogenic fungi and fungal like microbes: a comprehensive review on mechanisms, roles, and host interactions.Frontiers in plant science · 2025Review
- Fusarium Genome Sequencing and Assembly.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Fungal effectors: past, present, and future.Current opinion in microbiology · 2024Review
- Identification and Characterization of High-Molecular-Weight Proteins Secreted byJournal of fungi (Basel, Switzerland) · 2024Article
- Fusaric acid mediates the assembly of disease-suppressive rhizosphere microbiota via induced shifts in plant root exudates.Nature communications · 2024Article
- Molecular characterization of Indian races of Fusarium oxysporum f. sp. lentis (Fol) based on secreted in Xylem (SIX) effector genes and development of a SIX11 gene-based molecular marker for specific detection of Fol.Archives of microbiology · 2024Article
- Integrative omics studies revealed synergistic link between sucrose metabolic isogenes and carbohydrates in poplar roots infected by Fusarium wilt.Plant molecular biology · 2024Article
- Constitutive Overexpression of an NB-ARC Gene from Wild ChineseInternational journal of molecular sciences · 2024Article
- Small secreted effector protein from Fusarium sacchari suppresses host immune response by inhibiting ScPi21-induced cell death.Molecular plant pathology · 2024Article
- Pan-genome survey ofFrontiers in microbiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant pathogens use effector proteins to promote host colonisation. The mode of action of effectors from root-invading pathogens, such as Fusarium oxysporum (Fo), is poorly understood. Here, we investigated whether Fo effectors suppress pattern-triggered immunity (PTI), and whether they enter host cells during infection. Eight candidate effectors of an Arabidopsis-infecting Fo strain were expressed with and without signal peptide for secretion in Nicotiana benthamiana and their effect on flg22-triggered and chitin-triggered reactive oxidative species (ROS) burst was monitored. To detect uptake, effector biotinylation by an intracellular Arabidopsis-produced biotin ligase was examined following root infection. Four effectors suppressed PTI signalling; two acted intracellularly and two apoplastically. Heterologous expression of a PTI-suppressing effector in Arabidopsis enhanced bacterial susceptibility. Consistent with an intracellular activity, host cell uptake of five effectors, but not of the apoplastically acting ones, was detected in Fo-infected Arabidopsis roots. Multiple Fo effectors targeted PTI signalling, uncovering a surprising overlap in infection strategies between foliar and root pathogens. Extracellular targeting of flg22 signalling by a microbial effector provides a new mechanism on how plant pathogens manipulate their host. Effector translocation appears independent of protein size, charge, presence of conserved motifs or the promoter driving its expression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.