ArticleApplied clinical informatics2020
Sync for Genes: Making Clinical Genomics Available for Precision Medicine at the Point-of-Care.
Article in Applied clinical informatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- A Comprehensive Approach to Clinical Decision Support in the Return of Genome Informed Risk Assessments to Primary Care Pediatricians.Applied clinical informatics · 2025Article
- Enabling the clinical application of artificial intelligence in genomics: a perspective of the AMIA Genomics and Translational Bioinformatics Workgroup.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- The Case Manager: An Agent Controlling the Activation of Knowledge Sources in a FHIR-Based Distributed Reasoning Environment.Applied clinical informatics · 2023Article
- Challenges of Integrating APOL1 Genetic Test Results into the Electronic Health Record.Applied clinical informatics · 2023Article
- Introducing HL7 FHIR Genomics Operations: a developer-friendly approach to genomics-EHR integration.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- "fhircrackr": An R Package Unlocking Fast Healthcare Interoperability Resources for Statistical Analysis.Applied clinical informatics · 2023Article
- HL7 FHIR-based tools and initiatives to support clinical research: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- A qualitative investigation of biomedical informatics interoperability standards for genetic test reporting: benefits, challenges, and motivations from the testing laboratory's perspective.Genetics in medicine : official journal of the American College of Medical Genetics · 2021Article
- Fast-Tracking Health Data Standards Development and Adoption in Real-World Settings: A Pilot Approach.Applied clinical informatics · 2021Article
- Meeting the challenge: Health information technology's essential role in achieving precision medicine.Journal of the American Medical Informatics Association : JAMIA · 2021Article
- Celebrating Clinical Informatics as a Specialty Practice.Applied clinical informatics · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMaking genomic data available at the point-of-care and for research is critical for the success of the Precision Medicine Initiative (PMI), a research initiative which seeks to change health care by "tak(ing) into account individual differences in people's genes, environments, and lifestyles." The Office of the National Coordinator for Health Information Technology (ONC) led Sync for Genes, a program to develop standards that make genomic data available when and where it matters most. This article discusses lessons learned from recent Sync for Genes activities.
objectivesThe goals of Sync for Genes were to (1) demonstrate exchange of genomic data using health data standards, (2) provide feedback for refinement of health data standards, and (3) synthesize project experiences to support the integration of genomic data at the point-of-care and for research.
methodsFour organizations participated in a program to test the Health Level Seven International (HL7
resultsThe organizations successfully demonstrated exchange of genomic diagnostic reports using FHIR. The feedback and artifacts that resulted from these activities were shared with HL7 and made publicly available. Four areas were identified as important considerations for similar projects: (1) FHIR proficiency, (2) developer support, (3) project scope, and (4) bridging health information technology and genomic expertise.
conclusionPrecision medicine is a rapidly evolving field, and there is opportunity to continue maturing health data standards for the exchange of necessary genomic data, increasing the likelihood that the standard supports the needs of users.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.