Evidence map›Paper›PMID 32323173›Full record

ArticleJournal of community health2020

Examining Gender Differences in Lung Cancer Screening.

Simran Randhawa, Shelby R Sferra, Chandra Das, Larry R Kaiser, Grace X Ma, Cherie P Erkmen

Open access · greenAbstract read
In one paragraph

Article in Journal of community health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Sex Differences in Cancer Stage at Diagnosis of Nonreproductive Solid Organ Tumors in the United States, 2015 to 2022.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
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  6. Review
  7. Article
  8. Article
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  10. Article
  11. Disparities in thoracic surgical oncology.Journal of surgical oncology · 2023
    Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Simran RandhawaDepartment of Thoracic Surgery, Washington University, St. Louis, MO, USA.
Shelby R SferraDepartment of Surgery, Temple University Hospital, Philadelphia, PA, USA.
Chandra DasDepartment of Radiology, Lewis Katz School of Medicine, Philadelphia, PA, USA.
Larry R KaiserDepartment of Thoracic Surgery and Medicine, Lewis Katz School of MedicineTemple University, 3500 N Broad Street, Philadelphia, PA, 19140, USA.
Grace X MaCenter for Asian Health, Lewis Katz School of Medicine, Philadelphia, PA, USA.
Cherie P ErkmenDepartment of Thoracic Surgery and Medicine, Lewis Katz School of MedicineTemple University, 3500 N Broad Street, Philadelphia, PA, 19140, USA. Cherie.Erkmen@tuhs.temple.edu.
Temple University · USPhiladelphia University · USTemple University Hospital · USWashington University in St. Louis · US

Funding

TUFCCC/HC Regional Comprehensive Cancer Health PartnershipU54CA221704 · NCI · HUNTER COLLEGE · PI Joel Erblich · 2018 to 2026
$10.6M
NCI NIH HHS U54 CA221704
6 · The paper itself

Abstract

It is unknown if gender influences outcome of lung cancer screening with Low Dose CT (LDCT), especially with frequent and continued underrepresentation of women in clinical trials. We examined a balanced cohort of men and women with the hypothesis that there would be no difference in participation or results between men and women undergoing lung cancer screening. In an urban, academic medical center, we prospectively collected data on patients referred for lung cancer screening from October 2015 to August 2018. We studied gender, age, ethnicity, level of education and smoking history. We measured results of LDCT using Lung-RADS reporting system. 546 patients underwent LDCT between October 2015 and August 2018. 279 (51%) were female and 267 (49%) were males. Age, education status or smoking patterns did not significantly differ between females and males There was a significant difference between males and females in the distribution of LDCT results (p = 0.05). 81 females and 105 males were diagnosed with Lung-RADS 1; 99 females and 92 males with Lung-RADS 2; 15 females and 8 males with Lung-RADS 3; 19 females and 11 males with Lung-RADS 4. Overall, 10 females (3.5%) and 3 males (1.1%) were diagnosed with lung cancer (risk difference 2.4, 95% CI-0.0006-0.05, p = 0.09). Women are often underrepresented in clinical trials. Preliminary results from our lung cancer screening program demonstrate equal participation and equal benefit from the screening program. Long term data is needed to study survival benefit.

Indexed as

AgedEarly Detection of CancerFemaleHumansLung NeoplasmsMaleMiddle AgedSex FactorsTomography, X-Ray ComputedLow dose CT scanLung cancer screeningSmoking cessation

Identifiers

PMID32323173
PMCPMC7725370
OpenAlexW3019187958

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.