Evidence map›Paper›PMID 32323153›Full record

ArticleCellular and molecular neurobiology2021

Differential Contribution of Gap Junctions to the Membrane Properties of ON- and OFF-Bipolar Cells of the Rat Retina.

Rémi Fournel, Espen Hartveit, Margaret Lin Veruki

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rémi FournelDepartment of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway.ORCID http://orcid.org/0000-0003-2486-0307
Espen HartveitDepartment of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway. espen.hartveit@uib.no.ORCID http://orcid.org/0000-0003-1798-1901
Margaret Lin VerukiDepartment of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway. margaret.veruki@uib.no.ORCID http://orcid.org/0000-0002-0532-144X
University of Bergen · NO

Funding

European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 674901 674901The Research Council of Norway 182743The Research Council of Norway 189662The Research Council of Norway 214216The Research Council of Norway 261914
6 · The paper itself

Abstract

Gap junctions are ubiquitous within the retina, but in general, it remains to be determined whether gap junction coupling between specific cell types is sufficiently strong to mediate functionally relevant coupling via electrical synapses. From ultrastructural, tracer coupling and immunolabeling studies, there is clear evidence for gap junctions between cone bipolar cells, but it is not known if these gap junctions function as electrical synapses. Here, using whole-cell voltage-clamp recording in rat (male and female) retinal slices, we investigated whether the gap junctions of bipolar cells make a measurable contribution to the membrane properties of these cells. We measured the input resistance (R

Indexed as

Amacrine CellsAnimalsCell MembraneElectrophysiological PhenomenaFemaleGap JunctionsMaleMeclofenamic AcidRatsRetinal Bipolar CellsRetinal Rod Photoreceptor CellsMeclofenamic AcidCone bipolar cellsConnexin 36Connexin 45Electrical couplingGap junctionsRetina

Identifiers

PMID32323153
PMCPMC7870642
OpenAlexW3018374362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.