ArticleGeneral thoracic and cardiovascular surgery2020
Prognosis of patients with recurrence after pulmonary metastasectomy for colorectal cancer.
Article in General thoracic and cardiovascular surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- The Differential Diagnostic Value of Radiomics Signatures Between Single-Nodule Pulmonary Metastases and Second Primary Lung Cancer in Patients with Colorectal Cancer.Technology in cancer research & treatmentTrial
- Spread Through Air Spaces in Colorectal Lung Metastases Signals Local Recurrenece and Reflects Morphologic Aggressiveness of the Primary Tumor.Pathology international · 2026Article
- Importance of the ratio of surgical margin to nodule size in pulmonary metastasectomy for colorectal carcinoma.General thoracic and cardiovascular surgery · 2026Article
- Article
- SurvDB: Systematic Identification of Potential Prognostic Biomarkers in 33 Cancer Types.International journal of molecular sciences · 2025Article
- Review
- Results of intention-to-treat pulmonary metastasectomies in northern Finland revealing significant number of new lung primary carcinomas: time to move on from wedge resections?Journal of thoracic disease · 2023Article
- Article
- The İmportance of tumor markers in patients undergoing resection for lung metastasis of colorectal carcinoma.The clinical respiratory journal · 2023Article
- Fat signal fraction assessed with MRI predicts hepatic recurrence following hepatic resection for colorectal liver metastases.Langenbeck's archives of surgery · 2022Article
- Management of single pulmonary metastases from colorectal cancer: State of the art.World journal of gastrointestinal oncology · 2022Review
- Outcomes and Prognostic Factors of Patients with Metastatic Colorectal Cancer Who Underwent Pulmonary Metastasectomy with Curative Intent: A Brazilian Experience.The oncologist · 2021Article
- Novel strategy to treat lung metastases: Hybrid therapy involving surgery and radiofrequency ablation.Thoracic cancer · 2021Article
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3 authors at 1 institution in 1 country.
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Abstract
objectivesWe investigated the prognosis of patients with recurrence of pulmonary metastases (PM) from colorectal cancer (CRC) after resection.
methodsWe reviewed our surgical series of 101 CRC patients with PM who underwent R0 resection with curative intent. The overall survival (OS) and disease-free survival (DFS) rates after metastasectomy as well as the prognostic factors of survival were analyzed.
resultsFifty-five patients (54%) experienced recurrence, of whom 21 had developed extrapulmonary metastasis (EPM) before lung resection. Multivariate analysis restricted to patients with recurrence identified a disease-free interval (DFI) shorter than a year as an adverse prognosticator of OS (HR, 2.68; 95% CI 1.40-5.51; P < 0.01) and DFS (HR, 8.54; 95% CI 3.0-24.6; P < 0.001). EPM was also identified as an adverse prognosticator of OS for patients with recurrence (HR, 3.16; 95% CI 1.64-5.88; P < 0.001). There was a significant difference in the 5-year OS rate between patients with and without EPM (27.9% vs 64.9%, P < 0.001), and between those with a DFI shorter and longer than a year (40.0% vs 75.0%, P < 0.01). Among these, 31 patients (56%) bore lung-limited recurrence after their first lung resection, of whom 20 (36%) underwent a total of 29 repeat pulmonary metastasectomies, which resulted in a 5-year OS rate of 71.3% after the second lung resection.
conclusionsOur findings indicate that CRC patients with PM whose DFI is shorter than a year after lung resection or those with prior EPM more frequently experience multisite recurrence.
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