ReviewWorld journal of microbiology & biotechnology2020
Nature and bioprospecting of haloalkaliphilics: a review.
Review in World journal of microbiology & biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Metabolic adaptations of extremophiles and their applications in environmental biotechnology.World journal of microbiology & biotechnology · 2026Review
- Carboxydotrophic Acetogenesis in Alkaline Conditions Results in Transient Formate Production by the Halo-Alkaliphilic Acetogen Haloacetibacter carboxydivorans Gen. Nov. sp. Nov.Environmental microbiology reports · 2026Article
- Archaeal and Bacterial Communities Within the Wetland Alkaline Har Lake of the Qinghai-Xizang Plateau.Current microbiology · 2025Article
- Testing the Purity ofCells · 2025Article
- Microbial communities of selected regions of the Deep Springs Lake aquifer system.Frontiers in microbiology · 2025Article
- Metagenomic insights into the microbial community of the Buhera soda pans, Zimbabwe.BMC microbiology · 2024Article
- Integrated Genomics and Transcriptomics Provide Insights into Salt Stress Response inMicroorganisms · 2024Article
- Isolation and characterization of cellulose-mineralizing haloalkaliphilic bacteria from Siberian soda lakes.Frontiers in microbiology · 2024Article
- Halo-alkaliphilic microbes as an effective tool for heavy metal pollution abatement and resource recovery: challenges and future prospects.3 Biotech · 2023Review
- Bioprospecting of Actinobacterial Diversity and Antibacterial Secondary Metabolites from the Sediments of Four Saline Lakes on the Northern Tibetan Plateau.Microorganisms · 2023Article
- Modern Trends in Natural Antibiotic Discovery.Life (Basel, Switzerland) · 2023Review
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The haloalkaliphilics are an important subset of extremophiles that grow in salt [upto 33% (wt/vol) NaCl] and alkaline pH (> 9). They are found in hypersaline environments especially in the brines in arid, coastal and deep sea locations, and in alkaline environments, such as soda soils, lakes and deserts. Some authors have described haloalkaliphilic bacteria as moderate halophilic bacteria, but the molecular and classical studies revealed that they belong to moderately to extremely halophilic bacteria and archaea. Organic solutes, such as glycine, betaine and other amino acid derivatives, sugars such as, sucrose and trehalose, and sugar alcohols present in the haloalkaliphilics help for their osmoadaptation, and also serve as stabilizers. Haloalkalphilics secrete exoenzymes like proteases, amylases, xylanases, cellulases and peroxidases which have potential industrial applications. They also produce bacteriorhodopsin, compatible solutes, pigments, biopolymers, secondary metabolites like biosurfactants, polyhydroxyalkanoate (PHA) and exopolysaccharides and antimicrobial/anticancer compounds. They have unique metabolic pathways which can be used to treat industrial pollutants, heavy metals and waste water.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.