Evidence map›Paper›PMID 32322994›Full record

ArticleMikrochimica acta2020

Ultramarine blue nanoparticles as a label for immunochromatographic on-site determination of ractopamine.

Jing Liu, Qiongqiong Yu, Guangying Zhao, Wenchao Dou

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Research on Rapid Detection Technology forFoods (Basel, Switzerland) · 2022
    Article
  4. Review
  5. Fluorescent hollow ZrOMikrochimica acta · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jing LiuFood Safety Key Laboratory of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, 310018, China.
Qiongqiong YuFood Safety Key Laboratory of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, 310018, China.
Guangying ZhaoFood Safety Key Laboratory of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, 310018, China.
Wenchao DouSchool of Engineering, Westlake University, 18 Shilongshan Road, Hangzhou, 310024, China. wdou@zjsu.edu.cn.ORCID https://orcid.org/0000-0003-0999-012X
Zhejiang Gongshang University · CNWestlake University · CN

Funding

Natural Science Foundation of Zhejiang Province LY17C200003
6 · The paper itself

Abstract

A competitive immunochromatographic assay (ICA) is presented and used for on-site determination of ractopamine (RAC). Ultramarine blue nanoparticles were directly separated from ultramarine blue industrial products by centrifugation (< 10,000 rpm and > 4000 rpm) and used as visible labels in ICAs. The ultramarine blue nanoparticles were coated by polyacrylic acid (PAA), which provides carboxyl groups on the surface of ultramarine blue nanoparticles. An anti-RAC monoclonal antibody (mAb) was covalently immobilized on the carboxyl-modified ultramarine blue nanoparticle surface via diimide-activated conjugation between the carboxyl groups on the ultramarine blue nanoparticle surface and the amino groups of the antibodies. RAC and BSA-modified RAC competitively bind to the anti-RAC mAb on the ultramarine blue nanoparticles. The blue band in the test line is generated by the accumulation of ultramarine blue nanoparticles and is negatively associated with the RAC content. Under optimal conditions, the visual limit of detection (vLOD) of this ICA for RAC is 2.0 ng mL

Indexed as

AnimalsAntibodies, MonoclonalChromatography, AffinityFluorescent DyesMolecular StructureNanoparticlesParticle SizePhenethylaminesSurface PropertiesSwineAntibodies, MonoclonalFluorescent DyesPhenethylaminesractopamineImmunoassayImmunochromatographic assayLateral flow assayPigmentPoint-of-care testingPolyelectrolyteUltramarine blue nanoparticlesVisible markersβ-Agonists

Identifiers

PMID32322994
OpenAlexW3020317092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.