Evidence map›Paper›PMID 32322953›Full record

ArticleAnalytical and bioanalytical chemistry2020

Ability of selenium species to inhibit metal-induced Aβ aggregation involved in the development of Alzheimer's disease.

David Vicente-Zurdo, Iván Romero-Sánchez, Noelia Rosales-Conrado, María Eugenia León-González, Yolanda Madrid

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 44 citations in OpenAlex.

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  19. Alzheimer's Disease Association with Metals and Metalloids Concentration in Blood and Urine.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David Vicente-ZurdoDepartamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Iván Romero-SánchezDepartamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Noelia Rosales-ConradoDepartamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain.
María Eugenia León-GonzálezDepartamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Yolanda MadridDepartamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain. ymadrid@quim.ucm.es.
Universidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular accumulation of amyloid beta peptide (Aβ) is believed to be one of the main factors responsible for neurodegeneration in Alzheimer's disease (AD). Metals could induce Aβ aggregation, by their redox activity or binding properties to amyloid β fibrils, leading to their accumulation and deposition outside neurons. For this reason, metal chelation may have an acknowledged part to play in AD prevention and treatment. In the current work, the role of different selenium species, including selenium nanoparticles, in Aβ aggregation, was studied by evaluating their metal-chelating properties and their ability both to inhibit metal-induced Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAntioxidantsCopperHumansIronMetalsNanoparticlesProtein AggregatesProtein Aggregation, PathologicalSeleniumZincAmyloid beta-PeptidesAntioxidantsCopperIronMetalsProtein AggregatesSeleniumZincAlzheimer’s diseaseAntioxidant propertiesMetal-induced Aβ1–42 aggregationSelenium nanoparticlesSelenium species

Identifiers

PMID32322953
OpenAlexW3019636603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.