ArticleAdvances in radiation oncology
Management of Locally Advanced Rectal Cancer During The COVID-19 Pandemic: A Necessary Paradigm Change at Memorial Sloan Kettering Cancer Center.
Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Radiotherapy based management during Covid-19 pandemic - A systematic review of presented consensus and guidelines.Critical reviews in oncology/hematology · 2021Pooled it
- Total Neoadjuvant Therapy with FOLFOX Followed by Short-Course Radiation in Locally Advanced Rectal Cancer-An Alternative Approach Evaluated in a Single-Center Clinical Trial.Journal of clinical medicine · 2026Article
- Organ preservation after neoadjuvant long-course chemoradiotherapy versus short-course radiotherapy.Annals of oncology : official journal of the European Society for Medical Oncology · 2024Article
- Resilience in Rectal Cancer Treatment: Lessons from the COVID-19 Era in Czech Republic.Therapeutics and clinical risk management · 2024Article
- Functional Impairments in the Mental Health, Depression and Anxiety Related to the Viral Epidemic, and Disruption in Healthcare Service Utilization among Cancer Patients in the COVID-19 Pandemic Era.Cancer research and treatment · 2022Article
- The impact of COVID-19 on a high-volume incident learning system: A retrospective analysis.Journal of applied clinical medical physics · 2022Article
- Impact of COVID-19 pandemic on gastrointestinal cancer diagnosis and resection: An observational study.Clinics and research in hepatology and gastroenterology · 2022Observational
- Cost-effectiveness of Total Neoadjuvant Therapy With Short-Course Radiotherapy for Resectable Locally Advanced Rectal Cancer.JAMA network open · 2022Article
- Tailored treatment strategies for cancer patients during COVID-19 pandemic.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022Review
- The Validation Study of the Stress and Anxiety to Viral Epidemics-6 Scale Among Patients With Cancer in the COVID-19 Pandemic.Frontiers in psychiatry · 2022Article
- Watch-and-wait Management for Rectal Cancer After Clinical Complete Response to Neoadjuvant Therapy.Advances in surgery · 2021Review
- Lessons Learned in Managing Patients with Colorectal Cancer During the COVID-19 Pandemic.Current treatment options in oncology · 2021Review
- Radiotherapy management of rectal cancer in the backdrop of the COVID pandemic.Cancer reports (Hoboken, N.J.) · 2021Review
- A multi-institutional assessment of COVID-19-related risk in radiation oncology.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2020Article
- Breast, Prostate, and Rectal Cancer: Should 5-5-5 Be a New Standard of Care?International journal of radiation oncology, biology, physics · 2020Article
- Recommendations on Management of Locally Advanced Rectal Cancer During the COVID-19 Pandemic: an Iranian Consensus.Journal of gastrointestinal cancer · 2020Review
- [Impact of the pandemic on surgical activity in colorectal cancer in Spain. Results of a national survey].Cirugia espanola · 2020Article
- Hypofractionation in COVID-19 radiotherapy: A mix of evidence based medicine and of opportunities.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2020Article
- Review
- Cancer care and COVID-19: tailoring recommendations for the African radiation oncology context.Ecancermedicalscience · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
The COVID-19 pandemic will consume significant health care resources. Given the concerns for rapidly increasing infection rates in the United States, impending staffing shortages, and the potential for resource reallocation, we rapidly reevaluated our rectal cancer practice policies during this public health emergency. Before the pandemic, we commonly used total neoadjuvant therapy with a strong preference for long-course chemoradiation. In the setting of the ongoing pandemic, we now mandate short-course radiation therapy (SCRT). Despite multiple randomized trials demonstrating no difference in locoregional recurrence, distant recurrence, or overall survival between SCRT and long-course chemoradiation, the adaptation of SCRT in the United States has been low given concerns for less tumor downstaging and increased toxicity. In the setting of the ongoing and likely prolonged COVID-19 pandemic, we feel that these concerns must be reevaluated, because SCRT presents a well-validated alternative that will allow us to meet the needs of a greater number of potentially curable patients at a time when resources are severely and acutely constrained.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.