Evidence map›Paper›PMID 32322715›Full record

ArticleHeliyon2020

Impact of deoxycholate on

Yukino Usui, Alafate Ayibieke, Yuko Kamiichi, Shu Okugawa, Kyoji Moriya, Shuji Tohda, Ryoichi Saito

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Phenotypic analysis of variousApplied and environmental microbiology · 2025
    Article
  5. Article
  6. mSphere · 2025
    Article
  7. Phenotypic analysis of variousbioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Microbiology spectrum · 2023
    Article
  11. Potent Bile Acid Microbial Metabolites ModulatePathogens (Basel, Switzerland) · 2023
    Article
  12. Butyrate enhancesJournal of bacteriology · 2023
    Article
  13. Article
  14. Capturing the environment of the Clostridioides difficile infection cycle.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yukino UsuiDepartment of Molecular Microbiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Alafate AyibiekeDepartment of Molecular Microbiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Yuko KamiichiDepartment of Molecular Microbiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Shu OkugawaDepartment of Infectious Diseases, The University of Tokyo Hospital, Tokyo, Japan.
Kyoji MoriyaDepartment of Infectious Diseases, The University of Tokyo Hospital, Tokyo, Japan.
Shuji TohdaDepartment of Clinical Laboratory, Tokyo Medical and Dental University Medical Hospital, Tokyo, Japan.
Ryoichi SaitoDepartment of Molecular Microbiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Tokyo Medical and Dental University · JPUniversity of Tokyo Hospital · JPTokyo Medical and Dental University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBile acids play an important role in METHODOLOGY: Four genetically divergent

resultsWe found that DCA led to growth reduction in a dose-depended manner and regulated toxin production by repressing

conclusionsDCA modulates

Indexed as

BacteriologyClostridioides difficileDeoxycholateHepatobiliary systemInfectious diseaseMedical microbiologyMicrobiologyMicrobiology epidemiologySporulationToxin productionVegetative growth

Identifiers

PMID32322715
PMCPMC7160582
OpenAlexW3015653636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.