ReviewHeliyon2020
Childhood diarrhoeal diseases in developing countries.
Review in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05812820 (Research of Change of Microbial System Intestines and Efficacy for Probiotic Treatment of Persistent Diarrhea in Children), which is not on this map. Cited by 84 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Research of Change of Microbial System Intestines and Efficacy for Probiotic Treatment of Persistent Diarrhea in Children
Who cites it
84 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The Association Between Exclusive Breastfeeding and Diarrhoea Morbidity in Infants Aged 0-6 Months: A Rapid Review and Meta-Analysis.Maternal & child nutrition · 2025Pooled it
- Determinants of diarrhoeal diseases among under-five children in Africa (2013-2023): a comprehensive systematic review highlighting geographic variances, socioeconomic influences, and environmental factors.BMC public health · 2024Pooled it
- The relationship of vitamin D deficiency and childhood diarrhea: a systematic review and meta-analysis.BMC pediatrics · 2024Pooled it
- Burden of Childhood Diarrhea and Its Associated Factors in Ethiopia: A Review of Observational Studies.International journal of public health · 2024Pooled it
- Pooled it
- Article
- Similar Virulence Gene Repertoires but Distinct Stress Tolerance and Pathogenicity-Associated Phenotypes in RepresentativeMicroorganisms · 2026Article
- Regional disparities and predictors of childhood diarrhea in Ethiopia: a multilevel logistic regression analysis.BMC public health · 2026Article
- Development of Loop-Mediated Isothermal Amplification Assay for the Detection of aaic Positive Enteroaggregative Escherichia coli (EAEC).Applied biochemistry and biotechnology · 2026Article
- LEF1 gene mutation impairs the intestinal barrier and causes diarrhea.Molecular and cellular pediatrics · 2026Article
- Silent shedding of zoonotic enteric protozoa in domestic pigs for human consumption in selected farms in the Iberian Peninsula.Veterinary research communications · 2026Article
- Exclusive breastfeeding practices and challenges in Nigeria, Sub-Saharan Africa: an integrative review.International breastfeeding journal · 2026Review
- Detection of Cryptosporidium and Giardia duodenalis in Reptiles in Thailand.Veterinary medicine and science · 2026Article
- Viral diarrhea in Ghana: a scoping review of disease burden, epidemiology, and control strategies.Frontiers in public health · 2026Article
- Diet diversity during complementary feeding and childhood acute respiratory infection and diarrhoea in rural China.BMJ nutrition, prevention & health · 2026Article
- Diversity and Functional Predictions of Gut Microbiota in Vietnamese Children Aged 6-24 Months with Persistent Diarrhea of Unknown Etiology.Pathogens (Basel, Switzerland) · 2025Article
- [Global burden and predicted trends of diarrheal disease in children under five from 1990 to 2021].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- Surveillance of Common Circulating Enteric Bacteria and Antimicrobial Susceptibility Patterns in Five Satellite Laboratories in Rwanda, 2014-2022.The American journal of tropical medicine and hygiene · 2025Article
- Metagenomic identification of disease-causingMicrobial genomics · 2025Article
- Prevalence of ARI, fever, and diarrhea among under-five children and the influencing factors in southwestern coastal region of Bangladesh.BMC public health · 2025Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diarrhoeal diseases collectively constitute a serious public health challenge globally, especially as the leading cause of death in children (after respiratory diseases). Childhood diarrhoea affecting children under the age of five accounts for approximately 63% of the global burden. Accurate and timely detection of the aetiology of these diseases is very crucial; but conventional methods, apart from being laborious and time-consuming, often fail to identify difficult-to-culture pathogens. The aetiological agent of an average of up to 40% of cases of diarrhoea cannot be identified. This review gives an overview of the recent trends in the epidemiology and treatment of diarrhoea and aims at highlighting the potentials of metagenomics technique as a diagnostic method for enteric infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.