Evidence map›Paper›PMID 32322595›Full record

ArticleJournal of immunology research2020

Triggered Immune Response Induced by Antigenic Epitopes Covalently Linked with Immunoadjuvant-Pulsed Dendritic Cells as a Promising Cancer Vaccine.

Chumeng Chen, Mohanad Aldarouish, Qilong Li, Xiangzhen Liu, Feng Han, Hui Liu, Qijun Qian

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chumeng ChenXinyuan Institute of Medicine and Biotechnology, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Mohanad AldarouishShanghai Cell Therapy Research Institute, Shanghai 201805, China.ORCID https://orcid.org/0000-0001-9470-0224
Qilong LiShanghai Cell Therapy Research Institute, Shanghai 201805, China.
Xiangzhen LiuShanghai Cell Therapy Research Institute, Shanghai 201805, China.
Feng HanImmune Cell Division, Shanghai Cell Therapy Group, Shanghai 201805, China.
Hui LiuImmune Cell Division, Shanghai Cell Therapy Group, Shanghai 201805, China.
Qijun QianXinyuan Institute of Medicine and Biotechnology, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.ORCID https://orcid.org/0000-0002-3285-5009
Shanghai Cell Therapy Research Institute · CNZhejiang Sci-Tech University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The success of peptide-based dendritic cell (DC) cancer vaccines mainly depends on the utilized peptides and selection of an appropriate adjuvant. Herein, we aimed to evoke a broad immune response against multiple epitopes concurrently in the presence of immunoadjuvant. Three synthetic HLA-A∗0201-restricted peptides were separately linked with HMGB1-derived peptide (SAFFLFCSE, denoted as HB

Indexed as

Adjuvants, ImmunologicLymphocyte ActivationCancer VaccinesCell Line, TumorDendritic CellsEpitopes, T-LymphocyteHumansPancreatic NeoplasmsPeptidesT-Lymphocytes, CytotoxicAdjuvants, ImmunologicCancer VaccinesEpitopes, T-LymphocytePeptides

Identifiers

PMID32322595
PMCPMC7160722
OpenAlexW3014836949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.