Evidence map›Paper›PMID 32322420›Full record

ArticleJournal of advanced research2020

Targeted next generation sequencing identifies somatic mutations in a cohort of Egyptian breast cancer patients.

Auhood Nassar, Mohamed Abouelhoda, Osman Mansour, Samah A Loutfy, Mohamed M Hafez, M Gomaa, Abeer Bahnassy, Amira Salah El-Din Youssef, Mai M Lotfy, Hoda Ismail and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of advanced research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Auhood NassarCancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Mohamed AbouelhodaFaculty of Engineering, Cairo University, Cairo, Egypt.
Osman MansourMedical Oncology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Samah A LoutfyCancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Mohamed M HafezCancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
M GomaaRadiology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Abeer BahnassyPathology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Amira Salah El-Din YoussefCancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Mai M LotfyCancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Hoda IsmailPathology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Ola S AhmedCancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Amany Abd-Elhameed Abou-BakrPathology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Abdel-Rahman N ZekriCancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) incidence is progressively increasing in Egypt. However, there is insufficient knowledge of the acquired somatic mutations in Egyptian BC patients which limit our understanding of its progression. To the best of our knowledge, this is the first Egyptian cohort to sequence a multiple-gene panel of cancer related genes on BC patients. Four hundred and nine cancer related genes were sequenced in 46 fresh breast tumors of Egyptian BC patients to identify somatic mutations and their frequencies.

Indexed as

Breast cancerIon torrent sequencingNext Generation SequencingSomatic mutationsTarget sequencing

Identifiers

PMID32322420
PMCPMC7167517
OpenAlexW3014495258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.