Evidence map›Paper›PMID 32322334›Full record

ArticleOxidative medicine and cellular longevity2020

IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer.

Lei Zhang, Wen Liu, Fangyan Liu, Qun Wang, Mengjiao Song, Qi Yu, Kun Tang, Tieshan Teng, Dongdong Wu, Xijing Wang and 2 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 105 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 1 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 1 synthesis or guideline pooled it, 138 citations in OpenAlex.

  1. Review of ferroptosis in colorectal cancer: Friends or foes?World journal of gastroenterology · 2023
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45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Lei ZhangCell Signal Transduction Laboratory, Bioinformatics Center, Laboratory for Nanomedicine, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.ORCID https://orcid.org/0000-0002-7781-3478
Wen LiuCell Signal Transduction Laboratory, Bioinformatics Center, Laboratory for Nanomedicine, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Fangyan LiuCell Signal Transduction Laboratory, Bioinformatics Center, Laboratory for Nanomedicine, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Qun WangCell Signal Transduction Laboratory, Bioinformatics Center, Laboratory for Nanomedicine, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.ORCID https://orcid.org/0000-0002-1795-3604
Mengjiao SongCell Signal Transduction Laboratory, Bioinformatics Center, Laboratory for Nanomedicine, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Qi YuCell Signal Transduction Laboratory, Bioinformatics Center, Laboratory for Nanomedicine, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Kun TangCell Signal Transduction Laboratory, Bioinformatics Center, Laboratory for Nanomedicine, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Tieshan TengCell Signal Transduction Laboratory, Bioinformatics Center, Laboratory for Nanomedicine, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.ORCID https://orcid.org/0000-0002-2150-0261
Dongdong WuCell Signal Transduction Laboratory, Bioinformatics Center, Laboratory for Nanomedicine, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Xijing WangDepartment of Dermatology, Second People's Hospital of Zhengzhou, Zhengzhou 450006, China.
Wuqi HanKaifeng Food and Drug Inspection Institute, Kaifeng 475004, China.
Yanzhang LiCell Signal Transduction Laboratory, Bioinformatics Center, Laboratory for Nanomedicine, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.ORCID https://orcid.org/0000-0002-7327-0015
Henan University · CNXian Yang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis, implicated in several diseases, is a new form of programmed and nonapoptotic cell death triggered by iron-dependent lipid peroxidation after inactivation of the cystine/glutamate antiporter system xc

Identifiers

PMID32322334
PMCPMC7160732
OpenAlexW3015006353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.