Evidence map›Paper›PMID 32322331›Full record

ArticleRadiology case reports2020

Cerebral metastasis from osteosarcoma: "Bone" in the brain.

Stefania Kokkali, Efthymios Andriotis, Elena Katsarou, Angelos Theocharis, Maria Drizou, Elpida Magou, Alexandros Tzovaras, Alexandros Ardavanis

Open access · goldAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Stefania KokkaliFirst Medical Oncology Clinic, Saint-Savvas Cancer Hospital, L. Alexandras 171, 11522 Athens, Greece.
Efthymios AndriotisRadiology Department, Saint-Savvas Cancer Hospital, Athens, Greece.
Elena KatsarouFirst Medical Oncology Clinic, Saint-Savvas Cancer Hospital, L. Alexandras 171, 11522 Athens, Greece.
Angelos TheocharisFirst Medical Oncology Clinic, Saint-Savvas Cancer Hospital, L. Alexandras 171, 11522 Athens, Greece.
Maria DrizouFirst Medical Oncology Clinic, Saint-Savvas Cancer Hospital, L. Alexandras 171, 11522 Athens, Greece.
Elpida MagouFirst Medical Oncology Clinic, Saint-Savvas Cancer Hospital, L. Alexandras 171, 11522 Athens, Greece.
Alexandros TzovarasFirst Medical Oncology Clinic, Saint-Savvas Cancer Hospital, L. Alexandras 171, 11522 Athens, Greece.
Alexandros ArdavanisFirst Medical Oncology Clinic, Saint-Savvas Cancer Hospital, L. Alexandras 171, 11522 Athens, Greece.
St Savas Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although brain metastases from bone and soft tissue sarcoma are uncommon, advances in sarcoma treatment have led to an increasing incidence of them. We present a 23-year-old male with a history of metastatic femoral osteosarcoma, who presented with headache and unsteady gait and was diagnosed with a cerebellar metastasis. CT scan revealed a mass in the left cerebellar parenchyma with large intralesional central calcification and perilesional edema. Corticosteroid treatment led to neurological symptoms resolution, with a rapid tapering. The patient had also lung metastases and we opted to administer systemic treatment with the tyrosine kinase inhibitor cabozantinib. Given the relative radioresistance of osteosarcomas, the patient did not receive radiation therapy.

Indexed as

Brain metastasisCalcificationOsteosarcoma

Identifiers

PMID32322331
PMCPMC7171257
OpenAlexW3016551374

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.