ArticleInternational journal of microbiology2020
Antibacterial Activity of Rationally Designed Antimicrobial Peptides.
Article in International journal of microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
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- Directed Evolution of AtMP2 Peptide: Unlocking Enhanced Antibacterial Potential fromMolecules (Basel, Switzerland) · 2025Article
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- Cliotide U1, a Novel Antimicrobial Peptide Isolated FromBioinformatics and biology insights · 2025Article
- New-generation biofilm effective antimicrobial peptides and a real-time anti-biofilm activity assay: CoMIC.Applied microbiology and biotechnology · 2024Article
- New Insights into the Mechanism of Antibacterial Action of Synthetic PeptideAntibiotics (Basel, Switzerland) · 2022Article
- Impact of Electrospinning Parameters and Post-Treatment Method on Antibacterial and Antibiofilm Activity of Chitosan Nanofibers.Molecules (Basel, Switzerland) · 2022Article
- Discovery, Optimization, and Clinical Application of Natural Antimicrobial Peptides.Biomedicines · 2021Review
- Recent Advances in the Development of Antimicrobial and Antifouling Biocompatible Materials for Dental Applications.Materials (Basel, Switzerland) · 2021Review
- Regulatory mechanisms of sub-inhibitory levels antibiotics agent in bacterial virulence.Applied microbiology and biotechnology · 2021Review
- Molecular Basis of the Anticancer and Antibacterial Properties of CecropinXJ Peptide: An In Silico Study.International journal of molecular sciences · 2021Article
- The Antibacterial Activity of Crude Extracts of Secondary Metabolites from Bacterial Endophytes Associated withInternational journal of microbiology · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many infectious diseases are still prevalent in the world's populations since no effective treatments are available to eradicate them. The reasons may either be the antibiotic resistance towards the available therapeutic molecules or the slow rate of producing adequate therapeutic regimens to tackle the rapid growth of new infectious diseases, as well as the toxicity of current treatment regimens. Due to these reasons, there is a need to seek and develop novel therapeutic regimens to reduce the rapid scale of bacterial infections. Antimicrobial Peptides (AMPs) are components of the first line of defense for prokaryotes and eukaryotes and have a wide range of activities against Gram-negative and Gram-positive bacteria, fungi, cancer cells, and protozoa, as well as viruses. In this study, peptides which were initially identified for their HIV inhibitory activity were further screened for antibacterial activity through determination of their kinetics as well as their cytotoxicity. From the results obtained, the MICs of two AMPs (Molecule 3 and Molecule 7) were 12.5
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.