Evidence map›Paper›PMID 32322253›Full record

ArticleFrontiers in immunology2020

The Rules of Human T Cell Fate

Pedro Costa Del Amo, Bisrat Debebe, Milad Razavi-Mohseni, Shinji Nakaoka, Andrew Worth, Diana Wallace, Peter Beverley, Derek Macallan, Becca Asquith

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The dynamics and longevity of circulating CD4bioRxiv : the preprint server for biology · 2024
    Article
  5. Modeling T Cell Fate.Annual review of immunology · 2023
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Pedro Costa Del AmoDepartment of Infectious Disease, Imperial College London, London, United Kingdom.
Bisrat DebebeDepartment of Infectious Disease, Imperial College London, London, United Kingdom.
Milad Razavi-MohseniDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States.
Shinji NakaokaPrecursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency, Kawaguchi, Japan.
Andrew WorthThe Jenner Institute Laboratories, University of Oxford, Oxford, United Kingdom.
Diana WallaceDivision of Infection and Immunity, University College London, London, United Kingdom.
Peter BeverleyTB Research Centre, National Heart and Lung Research Institute, Imperial College London, London, United Kingdom.
Derek MacallanInstitute for Infection and Immunity, St. George's Hospital, University of London, London, United Kingdom.
Becca AsquithDepartment of Infectious Disease, Imperial College London, London, United Kingdom.
Imperial College London · GBJapan Science and Technology Agency · JPJenner Institute · GBJohns Hopkins University · USUniversity College London · GBUniversity of London · GB

Funding

Medical Research Council G1001052Medical Research Council J007439Medical Research Council MR/J007439/1Wellcome TrustWellcome Trust 103865
6 · The paper itself

Abstract

The processes governing lymphocyte fate (division, differentiation, and death), are typically assumed to be independent of cell age. This assumption has been challenged by a series of elegant studies which clearly show that, for murine cells

Indexed as

Models, TheoreticalCell DeathCell DifferentiationCell DivisionHumansT-Lymphocytesdecisionfatehalf-lifelabelinglifespanlymphocytemathematical modelproliferation

Identifiers

PMID32322253
PMCPMC7156550
OpenAlexW3015945615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.