Evidence map›Paper›PMID 32322201›Full record

ReviewFrontiers in pharmacology2020

Medicinal Plants as a Potential and Successful Treatment Option in the Context of Atherosclerosis.

Tatiana V Kirichenko, Vasily N Sukhorukov, Alexander M Markin, Nikita G Nikiforov, Ping-Yen Liu, Igor A Sobenin, Vadim V Tarasov, Alexander N Orekhov, Gjumrakch Aliev

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Cell death in atherosclerosis.Cell cycle (Georgetown, Tex.) · 2024
    Review
  9. Article
  10. Review
  11. Sitosterol-rich3 Biotech · 2023
    Article
  12. Article
  13. Effects of Moderate Intensity Aerobic Exercise to FSTL-1 Regulation in Atherosclerosis: A Systematic Review.The International journal of angiology : official publication of the International College of Angiology, Inc · 2023
    Review
  14. Review
  15. Key ingredients inFrontiers in plant science · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Atheroprotective Effects ofMolecules (Basel, Switzerland) · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tatiana V KirichenkoLaboratory of Infection Pathology and Molecular Microecology, Research Institute of Human Morphology, Moscow, Russia.
Vasily N SukhorukovLaboratory of Infection Pathology and Molecular Microecology, Research Institute of Human Morphology, Moscow, Russia.
Alexander M MarkinLaboratory of Infection Pathology and Molecular Microecology, Research Institute of Human Morphology, Moscow, Russia.
Nikita G NikiforovLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Ping-Yen LiuInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Igor A SobeninLaboratory of Infection Pathology and Molecular Microecology, Research Institute of Human Morphology, Moscow, Russia.
Vadim V TarasovSechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Alexander N OrekhovLaboratory of Infection Pathology and Molecular Microecology, Research Institute of Human Morphology, Moscow, Russia.
Gjumrakch AlievSechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a chronic multifactorial disease characterized by mainly changes of blood lipids profile and inflammation in vessel wall. The cardiovascular disease based on atherosclerosis is currently the leading cause of mortality in developed countries. Therefore, timely prevention and therapy of atherosclerosis are able to reduce the risk of the development of its clinical manifestations. Anti-atherosclerotic activity of medicinal plants mainly appears in their multiple effects such as anti-inflammatory, antioxidant, anti-atherogenic, hypotensive, lipid-lowering, anti-thrombotic. Moreover, most of medicinal plants are characterized by their pleiotropic anti-atherosclerotic action. In addition, the medicinal plants-derived pharmacological substances and/or compounds are characterized by relative safety and fewer side effects that allows considering them as one of potential anti-atherosclerotic effective agents. The direct anti-atherosclerotic effect of some medicinal plants was confirmed in clinical trials of carotid Intima-media thickness (IMT) progression during long-term medication with medicinal plants. This review attempted to determine the current status of the databases PubMed and Scopus (until November, 2019) to investigate the medicinal plants possessing anti-atherosclerotic activity in experimental and clinical studies.

Indexed as

anti-atherosclerotic mechanismsatherosclerosiscardiovascular riskcarotid IMTmedicinal plants

Identifiers

PMID32322201
PMCPMC7156611

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.