Evidence map›Paper›PMID 32322179›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Neck emphysema in a HNSCC cancer patient undergoing concurrent radiotherapy and cetuximab.

Valerio Nardone, Maria Grazia Calvanese, Ida D'Onofrio, Mario Di Stasio, Claudio Vitale, Antonia Silvestri, Bruno Daniele, Pierpaolo Correale, Paolo Fierro, Giuseppe Tortoriello and 3 more

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Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Valerio NardoneUnit of Radiation Oncology, Ospedale del Mare, Via E. Russo 1, 80147 Naples, Italy.
Maria Grazia CalvaneseUnit of Radiation Oncology, Ospedale del Mare, Via E. Russo 1, 80147 Naples, Italy.
Ida D'OnofrioUnit of Radiation Oncology, Ospedale del Mare, Via E. Russo 1, 80147 Naples, Italy.
Mario Di StasioUnit of Medical Oncology, Ospedale del Mare, Naples, Italy.
Claudio VitaleDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Antonia SilvestriUnit of Medical Oncology, Ospedale del Mare, Naples, Italy.
Bruno DanieleUnit of Medical Oncology, Ospedale del Mare, Naples, Italy.
Pierpaolo CorrealeUnit of Medical Oncology, Grand Metropolitan Hospital "Bianchi Melacrino Morelli", Reggio Calabria, Italy.
Paolo FierroUnit of Otorhinolaryngology, Ospedale del Mare, Naples, Italy.
Giuseppe TortorielloUnit of Otorhinolaryngology, Ospedale del Mare, Naples, Italy.
Alfonso ReginelliDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Salvatore CappabiancaDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Cesare GuidaUnit of Radiation Oncology, Ospedale del Mare, Via E. Russo 1, 80147 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung toxicity in patients undergoing cetuximab and radiotherapy (Cetux-RT) for head and neck squamous cell carcinoma (HNSCC) has been reported in literature and represents a serious side effect of concurrent therapies.

methodsWe report a case of a HNSCC patient that developed neck emphysema during the course of Cetux-RT. The patient was an old male (80 years old) in a good performance status, with an oropharyngeal cancer (T4aN3a).

resultsDuring RT, cone-beam computed tomography (CBCT) showed bilateral neck emphysema that was confirmed at restaging CT. We decided to stop the treatment and to treat the neck emphysema with conservative strategies. After one week CT was repeated and the neck emphysema had improved, so we decided to complete the RT treatment.

conclusionsPatients undergoing Cetux-RT must be properly selected, whereas IGRT imaging must be viewed carefully in order to permit an early diagnosis and careful management of the patients.

Indexed as

CetuximabHNSCCNeck emphysemaRadiation therapy

Identifiers

PMID32322179
PMCPMC7171259

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.