Evidence map›Paper›PMID 32322175›Full record

ReviewReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Prostatic irradiation-induced sexual dysfunction: a review and multidisciplinary guide to management in the radical radiotherapy era (Part I defining the organ at risk for sexual toxicities).

Marigdalia K Ramirez-Fort, Marc J Rogers, Roberto Santiago, Sean S Mahase, Melissa Mendez, Yi Zheng, Xiang Kong, James A Kashanian, M Junaid Niaz, Shearwood McClelland and 5 more

Abstract readReview
In one paragraph

Review in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. A tissue bandage for pelvic ganglia injury.Nature communications · 2024
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Prostatic irradiation-induced sexual dysfunction: A review and multidisciplinary guide to management in the radical radiotherapy era (Part II on Urological Management).Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Review
  12. Prostatic irradiation-induced sexual dysfunction: A review and multidisciplinary guide to management in the radical radiotherapy era (Part III on Psychosexual Therapy and the Masculine Self-Esteem).Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marigdalia K Ramirez-FortLife Sciences, BioFort Corp. Guaynabo, PR, United States.
Marc J RogersUrology, Medical University of South Carolina, Charleston, SC, United States.
Roberto SantiagoRadiation Oncology, Auxilio Mutuo, San Juan, PR, United States.
Sean S MahaseRadiation Oncology, Weill Cornell Medicine, New York, NY, United States.
Melissa MendezNeurology, SleepNet Neurology and Sleep Center, Bayamon, PR, United States.
Yi ZhengPhysics, JFK Comprehensive Cancer Institute, Lake Worth, FL, United States.
Xiang KongPhysics, JFK Comprehensive Cancer Institute, Lake Worth, FL, United States.
James A KashanianUrology, Weill Cornell Medicine, New York, NY, United States.
M Junaid NiazUrology, Weill Cornell Medicine, New York, NY, United States.
Shearwood McClellandRadiation Oncology, Indiana University, Indianapolis, IN, United States.
Xiaodong WuPhysics, JFK Comprehensive Cancer Institute, Lake Worth, FL, United States.
Neil H BanderUrology, Weill Cornell Medicine, New York, NY, United States.
Peter SchlegelUrology, Weill Cornell Medicine, New York, NY, United States.
John P MulhallSexual and Reproductive Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Christopher S LangeLife Sciences, BioFort Corp. Guaynabo, PR, United States.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Prostate cancer is the most common malignancy and the second leading cause of cancer-related death in men. Radiotherapy is a curative option that is administered via external beam radiation, brachytherapy, or in combination. Erectile, ejaculatory and orgasm dysfunction(s) is/are known potential and common toxicities associated with prostate radiotherapy. Our multidisciplinary team of physicians and/or scientists have written a three (3) part comprehensive review of the pathogenesis and management radiation-induced sexual dysfunction. Part I reviews pertinent anatomy associated with normal sexual function and then considers the pathogenesis of prostate radiation-induced sexual toxicities. Next, our team considers the associated radiobiological (including the effects of time, dose and fractionation) and physical (treatment planning and defining a novel Organ at Risk (OAR)) components that should be minded in the context of safe radiation treatment planning. The authors identify an OAR (i.e., the prostatic plexus) and provide suggestions on how to minimize injury to said OAR during the radiation treatment planning process.

Indexed as

Ejaculatory dysfunctionErectile dysfunctionOrgan at riskOrgasmic dysfunctionProstate cancerRadiation therapy

Identifiers

PMID32322175
PMCPMC7163290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.