Evidence map›Paper›PMID 32322167›Full record

ReviewMediators of inflammation2020

Mycobiome in the Gut: A Multiperspective Review.

Voon Kin Chin, Voon Chen Yong, Pei Pei Chong, Syafinaz Amin Nordin, Rusliza Basir, Maha Abdullah

Registry-linked trialAbstract readReview
In one paragraph

Review in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04447144 (Nutritional Habits, Does it Affect Coronavirus Disease 2019), which is not on this map. Cited by 87 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04447144 unknown statusnot on this map

Nutritional Habits, Does it Affect Coronavirus Disease 2019 (COVID-19) Infection Outcome? An Egyptian Experience

TypeobservationalSponsorCairo UniversityRan2020 to 2020Enrolled200ConditionsCovid19, Chronic Inflammation, Non-Communicable Chronic Diseases
3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  20. The Gut Mycobiome for Precision Medicine.Journal of fungi (Basel, Switzerland) · 2025
    Review

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Voon Kin ChinSchool of Biosciences, Faculty of Health and Medical Sciences, Taylor's University Lakeside Campus, 47500 Subang Jaya, Malaysia.ORCID https://orcid.org/0000-0003-4031-5851
Voon Chen YongSchool of Biosciences, Faculty of Health and Medical Sciences, Taylor's University Lakeside Campus, 47500 Subang Jaya, Malaysia.
Pei Pei ChongSchool of Biosciences, Faculty of Health and Medical Sciences, Taylor's University Lakeside Campus, 47500 Subang Jaya, Malaysia.
Syafinaz Amin NordinDepartment of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.ORCID https://orcid.org/0000-0002-6054-2368
Rusliza BasirDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.ORCID https://orcid.org/0000-0003-3363-6630
Maha AbdullahDepartment of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.ORCID https://orcid.org/0000-0003-2839-6273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human gut is home to a diverse and complex microbial ecosystem encompassing bacteria, viruses, parasites, fungi, and other microorganisms that have an undisputable role in maintaining good health for the host. Studies on the interplay between microbiota in the gut and various human diseases remain the key focus among many researchers. Nevertheless, advances in sequencing technologies and computational biology have helped us to identify a diversity of fungal community that reside in the gut known as the mycobiome. Although studies on gut mycobiome are still in its infancy, numerous sources have reported its potential role in host homeostasis and disease development. Nonetheless, the actual mechanism of its involvement remains largely unknown and underexplored. Thus, in this review, we attempt to discuss the recent advances in gut mycobiome research from multiple perspectives. This includes understanding the composition of fungal communities in the gut and the involvement of gut mycobiome in host immunity and gut-brain axis. Further, we also discuss on multibiome interactions in the gut with emphasis on fungi-bacteria interaction and the influence of diet in shaping gut mycobiome composition. This review also highlights the relation between fungal metabolites and gut mycobiota in human homeostasis and the role of gut mycobiome in various human diseases. This multiperspective review on gut mycobiome could perhaps shed new light for future studies in the mycobiome research area.

Indexed as

BacteriaFungiGastrointestinal MicrobiomeHumans

Identifiers

PMID32322167
PMCPMC7160717

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.