ArticleNature2020
The gut-brain axis mediates sugar preference.
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 170 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
170 citing papers in PubMed, 1 synthesis or guideline pooled it, 296 citations in OpenAlex.
- The effect of bariatric surgery on the expression of gastrointestinal taste receptors: A systematic review.Reviews in endocrine & metabolic disorders · 2024Pooled it
- Nutritional regulation of gut-brain immune crosstalk across the lifespan.Gut microbes · 2026Review
- A roadmap towards clinical use of molecular biomarkers in acute ischaemic stroke.Nature reviews. Neurology · 2026Review
- Precision nutrition for the prevention and management of inflammatory bowel disease.Nature reviews. Gastroenterology & hepatology · 2026Review
- Whole-brain, all-optical interrogation of neuronal dynamics underlying gut and vascular interoception in zebrafish.Nature communications · 2026Article
- The critical role of gut-brain signalling in eating behaviour and obesity.Nature reviews. Gastroenterology & hepatology · 2026Review
- Enteroendocrine cells wire the gut-brain vagal axis.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- High ambient temperature activates a neural circuit for gut glucose uptake in male mice.Nature communications · 2026Article
- Gut distension evokes rapid neural dynamics in vagal and hindbrain populations of larval zebrafish.iScience · 2026Article
- A distinct vagus-beta cell neural circuit senses glucose and modulates insulin secretion.Molecular metabolism · 2026Article
- Preference and behavioral responses to synbiotic supplementation via drinking water in laying hens under social stress.Poultry science · 2026Article
- From alpha diversity to zeitgebers: Functional implications and potential mechanisms linking the gut microbiome to sleep and circadian disruption (Part II).Neuroscience and biobehavioral reviews · 2026Review
- Article
- Early ingestive experience with a high-fat diet tunes satiation and nutrient-specific appetitive behaviors.bioRxiv : the preprint server for biology · 2026Article
- Mechanisms and clinical implications of gut-brain interactions.The Journal of clinical investigation · 2026Review
- Gut microbiomes-host immune response and organ dysfunction across the gut-lung, gut-brain, and gut-liver axes.Frontiers in cellular and infection microbiology · 2026Review
- AI digital-twin ecosystem translating gut-microbiome-neuroimmune signals into precision sleep-mood interventions.Frontiers in psychiatry · 2026Review
- The vagus nerve as a neurovisceral interface: a comprehensive review.Frontiers in neuroscience · 2026Review
- The gut vagal sensory pathway drives postprandial sleep via activation of PVH-projecting GABAergic neurons in the NTS.Nature communications · 2025Article
- Insular cortex predictions regulate glucose homeostasis.bioRxiv : the preprint server for biology · 2025Article
110 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
The taste of sugar is one of the most basic sensory percepts for humans and other animals. Animals can develop a strong preference for sugar even if they lack sweet taste receptors, indicating a mechanism independent of taste
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.