Evidence map›Paper›PMID 32321831›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Single-cell O

Sarah L Richardson, Alzbeta Hulikova, Melanie Proven, Ria Hipkiss, Magbor Akanni, Noémi B A Roy, Pawel Swietach

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Geometrical compartmentalization of trigger waves.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Addressing model discrepancy in a clinical model of the oxygen dissociation curve.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Article
  8. Article
  9. Hemoglobin as an oxygen gasoreceptor.Acta biochimica Polonica · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Autoregulation of HBritish journal of cancer · 2022
    Article
  16. Article
  17. Article
  18. OCellular and molecular life sciences : CMLS · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Sarah L RichardsonDepartment of Physiology, Anatomy & Genetics, University of Oxford, OX1 3PT Oxford, England.
Alzbeta HulikovaDepartment of Physiology, Anatomy & Genetics, University of Oxford, OX1 3PT Oxford, England.ORCID 0000-0001-8305-2890
Melanie ProvenMolecular Haematology Laboratory, Oxford University Hospitals National Health Service (NHS) Foundation Trust, John Radcliffe Hospital, OX3 9DS Oxford, England.
Ria HipkissMolecular Haematology Laboratory, Oxford University Hospitals National Health Service (NHS) Foundation Trust, John Radcliffe Hospital, OX3 9DS Oxford, England.
Magbor AkanniHaematology, Milton Keynes University Hospital, MK6 5LD Milton Keynes, England.ORCID 0000-0003-1864-1319
Noémi B A RoyMolecular Haematology Laboratory, Oxford University Hospitals National Health Service (NHS) Foundation Trust, John Radcliffe Hospital, OX3 9DS Oxford, England.
Pawel SwietachDepartment of Physiology, Anatomy & Genetics, University of Oxford, OX1 3PT Oxford, England; pawel.swietach@dpag.ox.ac.uk.ORCID 0000-0002-9945-9473
National Health Service · GBUniversity of Oxford · GBMilton Keynes Hospital · GB

Funding

British Heart Foundation RG/15/9/31534
6 · The paper itself

Abstract

Disorders of oxygen transport are commonly attributed to inadequate carrying capacity (anemia) but may also relate to inefficient gas exchange by red blood cells (RBCs), a process that is poorly characterized yet assumed to be rapid. Without direct measurements of gas exchange at the single-cell level, the barriers to O

Indexed as

AdultAgedBiological TransportCarbon DioxideCytoplasmErythrocytesFemaleGasesHealthy VolunteersHemoglobinsHumansMaleMiddle AgedOxygenSingle-Cell AnalysisCarbon DioxideGasesHemoglobinsOxygendiffusionerythrocytefluorescencegas channelsoxygen

Identifiers

PMID32321831
PMCPMC7211990
OpenAlexW3012651625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.