Evidence map›Paper›PMID 32321754›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Maternal T Cells in the Human Placental Villi Support an Allograft Response during Noninfectious Villitis.

Elizabeth Ann L Enninga, Patrick Raber, Reade A Quinton, Rodrigo Ruano, Nadia Ikumi, Clive M Gray, Erica L Johnson, Rana Chakraborty, Sarah E Kerr

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 41 citations in OpenAlex.

  1. Identification of proliferating CD103Virchows Archiv : an international journal of pathology · 2026
    Article
  2. Article
  3. Article
  4. Decidual CD4 Effector Memory and Resident Memory T Cells Respond to Cord Blood Allo-Antigens.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
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  11. Article
  12. Review
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  14. Review
  15. Immune surveillance of cytomegalovirus in tissues.Cellular & molecular immunology · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Elizabeth Ann L EnningaDepartment of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905; enninga.elizabethann@mayo.edu.ORCID 0000-0003-3621-7335
Patrick RaberAdaptive Biotechnologies, Seattle, WA 98102.ORCID 0000-0002-6050-1486
Reade A QuintonDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905.
Rodrigo RuanoDepartment of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905.ORCID 0000-0002-3642-5858
Nadia IkumiDivision of Immunology, Institute of Infectious Disease and Molecular Medicine, Department of Pathology, University of Cape Town, Cape Town, South Africa 7791.
Clive M GrayDivision of Immunology, Institute of Infectious Disease and Molecular Medicine, Department of Pathology, University of Cape Town, Cape Town, South Africa 7791.ORCID 0000-0002-9293-901X
Erica L JohnsonDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322.
Rana ChakrabortyDepartment of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905.ORCID 0000-0002-6585-0087
Sarah E KerrHospital Pathology Associates, Minneapolis, MN 55407.
Mayo Clinic · USUniversity of Cape Town · ZAAdaptive Biotechnologies (United States) · USEmory University · USMayo Clinic in Arizona · USMNGI Digestive Health · US

Funding

Mayo Clinic Interdisciplinary Women's Health Research ProgramK12HD065987 · NICHD · MAYO CLINIC ROCHESTER · PI KANTARCI, KEJAL · 2010 to 2023
$6.7M
Determining how macrophages regulate immunity to Zika virus infection at the maternal-fetal interfaceU01AI131566 · NIAID · EMORY UNIVERSITY · PI CHAKRABORTY, RANA, SUTHAR, MEHUL SHAMAL · 2017 to 2021
$2.3M
How maternal HCMV facilitates in utero transmission of HIV and impacts the developing fetal immune system during gestationR01HD097843 · NICHD · MOREHOUSE SCHOOL OF MEDICINE · PI CHAKRABORTY, RANA, JOHNSON, ERICA L · 2019 to 2021
$954k
Mechanisms by which trophoblasts recruit T cells to the placental villi during maternal HIV and CMV co-infectionR21HD103498 · NICHD · MAYO CLINIC ROCHESTER · PI CHAKRABORTY, RANA, GRAY, CLIVE MAURICE · 2020 to 2021
$390k
NIAID NIH HHS U01 AI131566NICHD NIH HHS K12 HD065987NICHD NIH HHS R01 HD097843NICHD NIH HHS R21 HD103498
6 · The paper itself

Abstract

During human pregnancy, proinflammatory responses in the placenta can cause severe fetal complications, including growth restriction, preterm birth, and stillbirth. Villitis of unknown etiology (VUE), an inflammatory condition characterized by the infiltration of maternal CD8

Indexed as

AdultAllograftsAntigens, ViralCell MovementChorionic VilliCohort StudiesEpitopes, T-LymphocyteFemaleFetusGenes, T-Cell Receptor betaGraft RejectionHLA AntigensHumansInflammationPlacenta DiseasesPregnancyAntigens, ViralEpitopes, T-LymphocyteHLA Antigens

Identifiers

PMID32321754
PMCPMC7307888
OpenAlexW3020079128

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.