Evidence map›Paper›PMID 32321582›Full record

ArticleMicrobiome2020

Isolation and characterization of diverse microbial representatives from the human skin microbiome.

Collin M Timm, Kristin Loomis, William Stone, Thomas Mehoke, Bryan Brensinger, Matthew Pellicore, Phillip P A Staniczenko, Curtisha Charles, Seema Nayak, David K Karig

Registry-linked trialAbstract readVideo-Audio Media
In one paragraph

Article in Microbiome, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05427760 (Effect of Using Oxygen on the Diaper Dermatitis in Infants), which is not on this map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05427760 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect of Using Oxygen on the Diaper Dermatitis in Infants

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2022 to 2023Enrolled103ConditionsDiaper Rash, Diaper DermatitisArmsOxygen
3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Skin bacteriota ameliorates androgenetic alopecia via harmonizing skin immuno inflammatory balance.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Skin microbiota and diabetic foot ulcers.Frontiers in microbiology · 2025
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Collin M TimmResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA.
Kristin LoomisResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA.
William StoneResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA.
Thomas MehokeResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA.
Bryan BrensingerResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA.
Matthew PellicoreResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA.
Phillip P A StaniczenkoBrooklyn College, City University of New York, Brooklyn, NY, USA.
Curtisha CharlesDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Seema NayakDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
David K KarigResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA. dkarig@clemson.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe skin micro-environment varies across the body, but all sites are host to microorganisms that can impact skin health. Some of these organisms are true commensals which colonize a unique niche on the skin, while open exposure of the skin to the environment also results in the transient presence of diverse microbes with unknown influences on skin health. Culture-based studies of skin microbiota suggest that skin microbes can affect skin properties, immune responses, pathogen growth, and wound healing.

resultsIn this work, we greatly expanded the diversity of available commensal organisms by collecting > 800 organisms from 3 body sites of 17 individuals. Our collection includes > 30 bacterial genera and 14 fungal genera, with Staphylococcus and Micrococcus as the most prevalent isolates. We characterized a subset of skin isolates for the utilization of carbon compounds found on the skin surface. We observed that members of the skin microbiota have the capacity to metabolize amino acids, steroids, lipids, and sugars, as well as compounds originating from personal care products.

conclusionsThis collection is a resource that will support skin microbiome research with the potential for discovery of novel small molecules, development of novel therapeutics, and insight into the metabolic activities of the skin microbiota. We believe this unique resource will inform skin microbiome management to benefit skin health. Video abstract.

Indexed as

BacteriaFungiMicrobiotaAdolescentAdultHealthy VolunteersHumansMiddle AgedSkinYoung AdultCarbon source utilizationIsolate collectionSkin microbiome

Identifiers

PMID32321582
PMCPMC7178971

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.