ArticleBMC ophthalmology2020
A study analyzing macular microvasculature features after vitrectomy using OCT angiography in patients with idiopathic macular epiretinal membrane.
Article in BMC ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- Prediction of visual acuity by macular distortion measured with optical coherence tomography angiography in epiretinal membranes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Morphologic assessment of photoreceptors after idiopathic epiretinal membrane surgery with adaptive-optics SLO.BMC ophthalmology · 2026Article
- Effect of Internal Limiting Membrane Peeling on Macular and Optic Disc Vascular Density Following Epiretinal Membrane Surgery.Beyoglu eye journal · 2026Article
- OCTA Biomarkers Underlying Structure-Function Correlations in Idiopathic Epiretinal Membrane: A Systematic Review.Diagnostics (Basel, Switzerland) · 2025Review
- Visual Function in Patients With Idiopathic Epiretinal Membrane Surgery: Evaluated by Microperimetry.Translational vision science & technology · 2025Article
- Effect of modified surgical conditions on the peripapillary microvasculature and RNFL in patients receiving vitrectomy: an OCTA study.BMC ophthalmology · 2025Article
- Assessment of clinical outcomes and prognostic factors following membrane peeling in idiopathic epiretinal membrane using EIFL staging system: an optical coherence tomography angiography analysis.BMC ophthalmology · 2025Article
- A classification of idiopathic epiretinal membrane based on foveal avascular zone area using optical coherence tomography angiography.Annals of medicine · 2024Article
- Association of Microvasculature Changes with Visual Outcomes in Idiopathic Epiretinal Membrane Surgery: A Clinical Trial.Journal of clinical medicine · 2024Article
- Peripapillary microvasculature changes after vitrectomy in epiretinal membrane via swept-source OCT angiography.BMC ophthalmology · 2023Article
- Total and horizontal distances of the foveal stereotaxic displacement can be prognostic indicators for patients with idiopathic epiretinal membrane.Frontiers in medicine · 2023Article
- Effect of Foveal Pit Restoration in Foveal Avascular Zone after Surgery for Idiopathic Epiretinal Membrane.Korean journal of ophthalmology : KJO · 2022Article
- Early Vascular and Functional Changes after Vitreoretinal Surgery: A Comparison between the Macular Hole and Epiretinal Membrane.Diagnostics (Basel, Switzerland) · 2021Article
- Macular Perfusion Impairment in Von Hippel-Lindau Disease Suggests a Generalized Retinal Vessel Alteration.Journal of clinical medicine · 2020Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundTo evaluate postoperative changes in retinal capillary plexus and to assess contributing factors in postoperative visual improvement using optical coherence tomography angiography (OCT-A) in patients with idiopathic epiretinal membrane (iERM) post membrane removal.
methodsPatients scheduled for vitrectomy and membrane peel for iERM were enrolled. 35 subjects were included for this study. OCT-A was used to measure the FAZ related parameters and the superficial and deep capillary plexus layers using 3 mm × 3 mm scans. Measurements were taken before surgery and at every post-surgical follow-up. The unaffected fellow eyes were used as controls. Evaluated factors included: BCVA, vessel density (VD) and retinal thickness (RT) in five regions, FAZ area, FAZ perimeter (PERIM), acircularity index (AI) and foveal vessel density (FD).
resultsCompared with the control group, the foveal vessel density (FVD) in superficial capillary plexus (SCP) was greater in the epi-retinal membrane group (P < 0.0001), whereas both groups had comparable parafoveal vessel density (PRVD) in SCP (p > 0.05). After surgery there was a reduction in the PRVD in SCP. The FVD in DCP increased and the PRVD in DCP decreased at baseline (p < 0.001). After surgery there was an increase in PRVD in DCP. By 6 months post-op, the PRVD had no statistically significant difference compared with the control group (p > 0.05). D-value of LogMAR BCVA was positively correlated with pre-op LogMAR BCVA (p < 0.0001), FVD in SCP (p < 0.001). It was negatively correlated with FAZ area (P < 0.001) and PERIM (P < 0.05).
conclusionsVitrectomy and membrane removal led to the decrease of VD in SCP and the increase of PRVD in DCP. Patients with a more severe iERM may receive greater visual improvement with surgery.
trial registrationTrial registration number (TRN) and date of registration. ChiCTR2000031289, retrospectively registered, 2020.03.26.
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