Evidence map›Paper›PMID 32321380›Full record

ArticleEmerging microbes & infections2020

IFITM3 affects the level of antibody response after influenza vaccination.

Na Lei, Yan Li, Qiang Sun, Jian Lu, Jianfang Zhou, Zi Li, Liqi Liu, Junfeng Guo, Kun Qin, Haibin Wang and 6 more

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Biology · 2026
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  4. mBio · 2025
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  13. Review
  14. Factors influencing the immunogenicity of influenza vaccines.Human vaccines & immunotherapeutics · 2021
    Review
  15. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Na LeiNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
Yan LiNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
Qiang SunNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
Jian LuNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
Jianfang ZhouNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
Zi LiNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
Liqi LiuNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
Junfeng GuoNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
Kun QinNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
Haibin WangChaoyang District Center for Disease Prevention and Control, Beijing, People's Republic of China.
Jianhong ZhaoChaoyang District Center for Disease Prevention and Control, Beijing, People's Republic of China.
Chong LiChaoyang District Center for Disease Prevention and Control, Beijing, People's Republic of China.
Lingli SunChaoyang District Center for Disease Prevention and Control, Beijing, People's Republic of China.
Dayan WangNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
Zhendong ZhaoNHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
Yuelong ShuNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Prevention and Control, Beijing, People's Republic of China.
National Institute for Viral Disease Control and Prevention · CNBeijing Center for Disease Prevention and Control · CNSun Yat-sen University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferon-induced transmembrane protein 3 (IFITM3) as an antiviral factor can inhibit replication of several viruses including influenza virus. A single-nucleotide polymorphism rs12252-C of

Indexed as

Membrane ProteinsRNA-Binding ProteinsAdaptive ImmunityAdolescentAdultAnimalsAntibodies, ViralAntibody FormationAsian PeopleFemaleGenetic Predisposition to DiseaseGenotypeHumansInfluenza A virusInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeAntibodies, Viralfragilis protein, mouseIFITM3 protein, humanInfluenza VaccinesMembrane ProteinsRNA-Binding ProteinsIFITM3immune responseinfluenza virusInterferon-induced transmembrane protein 3SNP rs12252trivalent inactivated vaccine

Identifiers

PMID32321380
PMCPMC7269036
OpenAlexW3017854185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.