Evidence map›Paper›PMID 32321353›Full record

ArticleJournal of the American Psychiatric Nurses Association

Improvement of Autism Symptoms After Comprehensive Intensive Early Interventions in Community Settings.

Nils Haglund, SvenOlof Dahlgren, Maria Råstam, Peik Gustafsson, Karin Källén

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Psychiatric Nurses Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Overall prognosis of preschool autism spectrum disorder diagnoses.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nils HaglundNils Haglund, PhD, Lund University, Lund, Sweden.ORCID 0000-0002-4781-7777
SvenOlof DahlgrenSvenOlof Dahlgren, PhD, University of Gothenburg, Gothenburg, Sweden.
Maria RåstamMaria Råstam, MD, Lund University, Lund, Sweden; University of Gothenburg, Gothenburg, Sweden.
Peik GustafssonPeik Gustafsson, MD, Lund University, Lund, Sweden.
Karin KällénKarin Källén, PhD, Lund University, Lund, Sweden.
Lund University · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreschool children with autism in southern Sweden participated in a comprehensive Naturalistic Developmental Behavioral Intervention (NDBI) program.

aimsTo evaluate the ongoing NDBI program by comparing the pre- and postintervention outcomes in terms of improved autism symptom severity.

methodThe improvement of Autism Diagnostic Observation Schedule (ADOS-R) test results between baseline and evaluation among children participating in the NDBI program (

resultsThe study showed that children in the NDBI group improved their ADOS-R total scores between baseline and evaluation (-0.8 scores per year; 95% CI [-1.2, -0.4]), whereas no improvement was detected in the comparison group (+0.1 scores per year; 95% CI [-0.7, +0.9]). The change in the NDBI group versus the change in the comparison group was statistically significant after adjusting for possible confounders as well. Children in the NDBI group also significantly improved their ADOS severity scores, but the scores were not significantly different from those of the comparison group.

conclusionsThe results from the current naturalistic study must be interpreted cautiously, but they do support earlier studies reporting on improvement of autism symptoms after early intensive interventions. Results from observational studies are difficult to interpret, but it is nevertheless of uttermost importance to evaluate costly autism intervention programs. The results do indicate that children with autism benefit from participating in early comprehensive intensive programs.

Indexed as

Autism Spectrum DisorderAutistic DisorderBehavior TherapyChild, PreschoolEarly Intervention, EducationalHumansLongitudinal StudiesADOS scoresautism symptomsintervention program

Identifiers

PMID32321353
PMCPMC8581718
OpenAlexW3020062894

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.