ArticleRevista da Sociedade Brasileira de Medicina Tropical2020
Adverse drug events and the associated factors in patients with chronic Chagas disease.
Article in Revista da Sociedade Brasileira de Medicina Tropical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Chagas heart disease: An overview of diagnosis, manifestations, treatment, and care.World journal of cardiology · 2021Review
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Authors and funding
12 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHerein, we aimed to identify the factors associated with adverse drug events (ADEs) in chronic Chagas disease (CD) patients.
methodsWe analyzed 320 medical notes from 295 patients. The Naranjo algorithm was applied to determine the cause of ADEs. Mixed effects logistic regression was performed to evaluate the factors associated with ADEs.
resultsADEs were described in 102 medical notes (31.9%). Captopril was most frequently associated with ADEs. Age (RR 0.96; 95%CI 0.94-0.99) and cardiac C/D stages (RR 3.24; 95%CI 1.30-4.58) were the most important clinical factors associated with ADEs.
conclusionsClose follow-up is warranted for CD patients.
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