Evidence map›Paper›PMID 32320764›Full record

ArticleJournal of the American Academy of Dermatology2020

Functional status and survival in patients ≥85 years of age who have keratinocyte carcinoma: A retrospective cohort study.

Niki B Vora, Karen L Connolly, Stephen Dusza, Anthony M Rossi, Kishwer S Nehal, Erica H Lee

Abstract read
In one paragraph

Article in Journal of the American Academy of Dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Niki B VoraDepartment of Dermatology, University of California, San Francisco, California.
Karen L ConnollyPrivate Practice, West Orange, New Jersey.
Stephen DuszaDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Anthony M RossiDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Kishwer S NehalDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Erica H LeeDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: leee@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Summer research experiences for medical students supervised by faculty mentorsR25CA020449 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Charlotte Eielson Ariyan · 1985 to 2026
$6.2M
NCI NIH HHS P30 CA008748NCI NIH HHS R25 CA020449
6 · The paper itself

Abstract

backgroundFunctional status assessment may help estimate which patients ≥85 years of age will benefit from surgical treatment for keratinocyte carcinoma (KC), but predictive value for short-term survival in this population has not been determined.

objectiveWe sought to assess the predictive value of functional status for short-term survival in patients ≥85 years of age who have KC.

methodsThis was a retrospective cohort review of 238 patients ≥85 years of age who presented for the management of KC between 2010 and 2015. Functional status was assessed with the Karnofsky Performance Scale (KPS) and Katz Activities of Daily Living (ADL) index. Overall survival was determined.

resultsLower functional status scores of KPS ≤40 and Katz ADL ≤4 were associated with 37% and 53% survival at 2 years, respectively. LIMITATIONS: Retrospective design and single-center study.

conclusionIn this study, KPS and Katz ADL predicted short-term survival. Patients with low functional status scores had significantly decreased survival at 2 years, with double the death rate of patients with high functional status. Functional status should be considered during shared decision-making for elderly individuals who are seeking treatment for KC.

Indexed as

Functional StatusAged, 80 and overAge FactorsBasal Cell CarcinomaCarcinoma, Squamous CellFeasibility StudiesFemaleFollow-Up StudiesHumansKaplan-Meier EstimateKarnofsky Performance StatusKeratinocytesMalePredictive Value of TestsRetrospective StudiesRisk Assessmentfunctional assessmentgeriatricsKarnofsky Performance ScaleKatz ADLkeratinocyte carcinomaoncology

Identifiers

PMID32320764
PMCPMC7377923

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.