Evidence map›Paper›PMID 32320318›Full record

ReviewMolecular biology of the cell2020

The ABCF gene family facilitates disaggregation during animal development.

Sydney Skuodas, Amy Clemons, Michael Hayes, Ashley Goll, Betul Zora, Daniel L Weeks, Bryan T Phillips, Jan S Fassler

Abstract readReview
In one paragraph

Review in Molecular biology of the cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sydney SkuodasDepartment of Biology, University of Iowa, Iowa City, IA 52242.
Amy ClemonsDepartment of Biology, University of Iowa, Iowa City, IA 52242.
Michael HayesDepartment of Biochemistry, University of Iowa, Iowa City, IA 52242.
Ashley GollDepartment of Biochemistry, University of Iowa, Iowa City, IA 52242.
Betul ZoraDepartment of Biology, University of Iowa, Iowa City, IA 52242.
Daniel L WeeksDepartment of Biochemistry, University of Iowa, Iowa City, IA 52242.
Bryan T PhillipsDepartment of Biology, University of Iowa, Iowa City, IA 52242.
Jan S FasslerDepartment of Biology, University of Iowa, Iowa City, IA 52242.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007337 · NIGMS · UNIVERSITY OF IOWA · PI GEYER, PAMELA K., LENTZ, STEVEN R · 1985 to 2020
$15.9M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Novel Beta-catenin Regulatory Mechanisms in C. elegans Asymmetric Cell DivisionsR01GM114007 · NIGMS · UNIVERSITY OF IOWA · PI PHILLIPS, BRYAN T · 2016 to 2020
$1.5M
Amyloids, aggregates and Nucleolar activity in Xenopus developmentR01GM124063 · NIGMS · UNIVERSITY OF IOWA · PI WEEKS, DANIEL L. · 2018 to 2021
$1.3M
National Science Foundation IOS-1456941NIGMS NIH HHS R01 GM114007NIGMS NIH HHS R01 GM124063NIGMS NIH HHS T32 GM007337NIH HHS P40 OD010440
6 · The paper itself

Abstract

Protein aggregation, once believed to be a harbinger and/or consequence of stress, age, and pathological conditions, is emerging as a novel concept in cellular regulation. Normal versus pathological aggregation may be distinguished by the capacity of cells to regulate the formation, modification, and dissolution of aggregates. We find that

Indexed as

Embryonic DevelopmentProtein Aggregation, PathologicalAnimalsATP-Binding Cassette TransportersHumansATP-Binding Cassette Transporters

Identifiers

PMID32320318
PMCPMC7353142

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.