Evidence map›Paper›PMID 32320265›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2020

Interleukin-17 signaling mediates cytolytic natural killer cell activation in response to placental ischemia.

Olivia K Travis, Dakota White, Cedar Baik, Chelsea Giachelli, Willie Thompson, Cassandra Stubbs, Mallory Greer, James P Lemon, Jan Michael Williams, Denise C Cornelius

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Interleukin-1 receptor type 1 inhibition improves blood pressure, fetal growth and immune balance in placental ischemic rats.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. IL-33 Signaling Inhibition Leads to a Preeclampsia-Like Phenotype in Pregnant Rats.American journal of reproductive immunology (New York, N.Y. : 1989) · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. VASCULAR AND RENAL MECHANISMS OF PREECLAMPSIA.Current opinion in physiology · 2023
    Article
  16. NLRP3 inhibition improves maternal hypertension, inflammation, and vascular dysfunction in response to placental ischemia.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Article
  17. Inhibiting B cell activating factor attenuates preeclamptic symptoms in placental ischemic rats.American journal of reproductive immunology (New York, N.Y. : 1989) · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Olivia K TravisDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.ORCID 0000-0001-7392-9054
Dakota WhiteDepartment of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Cedar BaikDepartment of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Chelsea GiachelliDepartment of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Willie ThompsonDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
Cassandra StubbsDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
Mallory GreerDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
James P LemonDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
Jan Michael WilliamsDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
Denise C CorneliusDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.ORCID 0000-0002-6730-6499
University of Mississippi Medical Center · US

Funding

Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Pier Paolo Claudio, Babbette LaMarca · 2017 to 2026
$26.4M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, JOHN E · 2013 to 2022
$23.4M
Hypertension and Cardiorenal Research Training ProgramT32HL105324 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI Joey P. Granger · 2010 to 2026
$7.8M
Mechanisms involved in the early development of renal disease associated with prepubertal obesityR01DK109133 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI WILLIAMS, JAN MICHAEL · 2017 to 2021
$1.7M
Hypertension and InflammationR00HL130456 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2017 to 2019
$747k
HHS | NIH | National Heart, Lung, and Blood Institute (NHBLI) R00HL130456HHS | NIH | National Heart, Lung, and Blood Institute (NHBLI) T32HL105324HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01DK109133HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM104357NHLBI NIH HHS R00 HL130456NHLBI NIH HHS T32 HL105324NIDDK NIH HHS R01 DK109133NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20 GM121334
6 · The paper itself

Abstract

T-helper (T

Indexed as

AnimalsArterial PressureCytokinesFemaleInflammation MediatorsInterleukin-17IschemiaKiller Cells, NaturalPlacentaPregnancyRatsRats, Sprague-DawleyReactive Oxygen SpeciesReceptors, Interleukin-17Th17 CellsCytokinesInflammation MediatorsInterleukin-17Reactive Oxygen SpeciesReceptors, Interleukin-17hypertensionIL-17natural killer cellsplacental ischemiapreeclampsia

Identifiers

PMID32320265
PMCPMC7311683
OpenAlexW3016634006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.