Evidence map›Paper›PMID 32320259›Full record

ArticleOrganic letters2020

Rh-Catalyzed Aziridine Ring Expansions to Dehydropiperazines.

Hillary J Dequina, Josephine Eshon, William T Raskopf, Israel Fernández, Jennifer M Schomaker

RetractedAbstract readRetracted Publication
In one paragraph

Article in Organic letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Hillary J DequinaDepartment of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.
Josephine EshonDepartment of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.
William T RaskopfDepartment of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.
Israel FernándezDepartamento de Orgánica I and Centro de en Quı́mica Avazanda (ORFEO-CINQA), Facultad de Ciencias, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-0186-9774
Jennifer M SchomakerDepartment of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.ORCID 0000-0003-1329-950X

Funding

Versatile complex amine synthesis via aziridinium ylides and 2-amidoallyl cationsR01GM132300 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SCHOMAKER, JENNIFER MARIE · 2019 to 2022
$1.5M
QExactive (Orbitrap) mass spectrometerS10OD020022 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI VESTLING, MARTHA M · 2015 to 2015
$483k
NMR SPECTROMETERS10RR008389 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI VEDEJS, EDWIN · 1993 to 1993
–
NCRR NIH HHS S10 RR008389NIGMS NIH HHS R01 GM132300NIH HHS S10 OD020022
6 · The paper itself

Abstract

Piperazines are prevalent in pharmaceuticals and natural products, but traditional methods do not typically introduce stereochemical complexity into the ring. To expand access to these scaffolds, we report Rh-catalyzed ring expansions of aziridines and

Indexed as

AziridinesCatalysisIminesMolecular StructureNitrilesPiperazinesRhodiumTriazolesAziridinesIminesketimineNitrilesPiperazinesRhodiumTriazoles

Identifiers

PMID32320259
PMCPMC8025198

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.