Evidence map›Paper›PMID 32319849›Full record

ArticleJournal of neurophysiology2020

Abnormal development of auditory responses in the inferior colliculus of a mouse model of Fragile X Syndrome.

Anna O Nguyen, Devin K Binder, Iryna M Ethell, Khaleel A Razak

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Auditory processing in rodent models of autism: a systematic review.Journal of neurodevelopmental disorders · 2022
    Pooled it
  2. Pooled it
  3. bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Altered Auditory Maturation in Fragile X Syndrome and Its Involvement in Audiogenic Seizure Susceptibility.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Mouse models of fragile X-related disorders.Disease models & mechanisms · 2023
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. The Inferior Colliculus in Alcoholism and Beyond.Frontiers in systems neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anna O NguyenBioengineering Program, University of California, Riverside, California.
Devin K BinderGraduate Neuroscience Program, University of California, Riverside, California.
Iryna M EthellGraduate Neuroscience Program, University of California, Riverside, California.
Khaleel A RazakGraduate Neuroscience Program, University of California, Riverside, California.
University of California, Riverside · US

Funding

Neurophysiological and acute pharmacological studies in FXS patientsU54HD082008 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI HUBER, KIMBERLY M. · 2014 to 2019
$9.8M
NICHD NIH HHS U54 HD082008
6 · The paper itself

Abstract

Sensory processing abnormalities are frequently associated with autism spectrum disorders, but the underlying mechanisms are unclear. Here we studied auditory processing in a mouse model of Fragile X Syndrome (FXS), a leading known genetic cause of autism and intellectual disability. Both humans with FXS and the

Indexed as

AnimalsAuditory Perceptual DisordersDisease Models, AnimalElectrophysiological PhenomenaEpilepsy, ReflexFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeInferior ColliculiMaleMiceMice, KnockoutNeuronsFmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1autismdevelopmentFragile X Syndromeinferior colliculusseizuressensory hypersensitivity

Identifiers

PMID32319849
PMCPMC7474255
OpenAlexW3017211877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.