ArticleJournal of neurophysiology2020
Cortical processing of chemosensory and hedonic features of taste in active licking mice.
Article in Journal of neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Article
- Neural coding in gustatory cortex reflects consumption decisions: evidence from conditioned taste aversion.Frontiers in systems neuroscience · 2026Article
- Linear and categorical coding units in the mouse gustatory cortex drive population dynamics and behavior in taste decision-making.bioRxiv : the preprint server for biology · 2025Article
- Deficits in taste-guided behaviors and central processing of taste in the transgenic TDP-43Neurobiology of disease · 2025Article
- Neural Processing of Taste-Related Signals in the Mediodorsal Thalamus of Mice.bioRxiv : the preprint server for biology · 2025Article
- Cortical coding of gustatory and thermal signals in active licking mice.The Journal of physiology · 2025Article
- Cortical Coding of Gustatory and Thermal Signals in Active Licking Mice.bioRxiv : the preprint server for biology · 2024Article
- Multisensory Integration Underlies the Distinct Representation of Odor-Taste Mixtures in the Gustatory Cortex of Behaving Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Learning enhances representations of taste-guided decisions in the mouse gustatory insular cortex.Current biology : CB · 2024Article
- Neural Activity in the Anterior Insula at Drinking Onset and Licking Relates to Compulsion-Like Alcohol Consumption.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Glucagon-Like Peptide-1 Receptors in the Gustatory Cortex Influence Food Intake.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Temporal progression along discrete coding states during decision-making in the mouse gustatory cortex.PLoS computational biology · 2023Article
- Oral thermal processing in the gustatory cortex of awake mice.Chemical senses · 2023Article
- The impact of familiarity on cortical taste coding.Current biology : CB · 2022Article
- Active Licking Shapes Cortical Taste Coding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- LiCl-induced sickness modulates rat gustatory cortical responses.PLoS biology · 2022Article
- Trehalose Reduces Nerve Injury Induced Nociception in Mice but Negatively Affects Alertness.Nutrients · 2021Article
- Spatially Distributed Representation of Taste Quality in the Gustatory Insular Cortex of Behaving Mice.Current biology : CB · 2021Article
- A drivable optrode for use in chronic electrophysiology and optogenetic experiments.Journal of neuroscience methods · 2021Article
- Cortical Hub for Flavor Sensation in Rodents.Frontiers in systems neuroscience · 2021Review
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2 authors.
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Abstract
In the last two decades, a considerable amount of work has been devoted to investigating the neural processing and dynamics of the primary taste cortex of rats. Surprisingly, much less information is available on cortical taste electrophysiology in awake mice, an animal model that is taking on a more prominent role in taste research. Here we present electrophysiological evidence demonstrating how the gustatory cortex (GC) encodes the basic taste qualities (sweet, salty, sour, and bitter) and water when stimuli are actively sampled through licking, the stereotyped behavior by which mice control the access of fluids in the mouth. Mice were trained to receive each stimulus on a fixed ratio schedule in which they had to lick a dry spout six times to receive a tastant on the seventh lick. Electrophysiological recordings confirmed that GC neurons encode both chemosensory and hedonic aspects of actively sampled tastants. In addition, our data revealed two other main findings: GC neurons rapidly encode information about taste qualities in as little as 120 ms, and nearly half of the recorded neurons exhibit spiking activity entrained to licking at rates up to 8 Hz. Overall, our results highlight how the GC of active licking mice rapidly encodes information about taste qualities as well as ongoing sampling behavior, expanding our knowledge on cortical taste processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.