Evidence map›Paper›PMID 32319135›Full record

ArticlePaediatric and perinatal epidemiology2020

Risk of selection bias due to non-participation in a cohort study on pubertal timing.

Nis Brix, Andreas Ernst, Lea Lykke Braskhøj Lauridsen, Erik Thorlund Parner, Onyebuchi A Arah, Jørn Olsen, Tine Brink Henriksen, Cecilia Høst Ramlau-Hansen

Open access · hybridAbstract read
In one paragraph

Article in Paediatric and perinatal epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Nis BrixDepartment of Public Health, Research Unit for Epidemiology, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-1499-8401
Andreas ErnstDepartment of Public Health, Research Unit for Epidemiology, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-5533-8891
Lea Lykke Braskhøj LauridsenDepartment of Public Health, Research Unit for Epidemiology, Aarhus University, Aarhus, Denmark.
Erik Thorlund ParnerDepartment of Public Health, Research Unit for Biostatistics, Aarhus University, Aarhus, Denmark.
Onyebuchi A ArahDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Jørn OlsenDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Tine Brink HenriksenPerinatal Epidemiology Research Unit, Department of Paediatrics, Aarhus University Hospital, Aarhus, Denmark.
Cecilia Høst Ramlau-HansenDepartment of Public Health, Research Unit for Epidemiology, Aarhus University, Aarhus, Denmark.
University of California, Los Angeles · USAarhus University · DKAarhus University Hospital · DK

Funding

Scientific and Technical CoreP2CHD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HIRAM BELTRAN-SANCHEZ · 2016 to 2026
$6.9M
NICHD NIH HHS P2C HD041022
6 · The paper itself

Abstract

backgroundNon-participation in aetiologic studies of pubertal timing is frequent. However, little effort has been given to explore the risk and potential impact of selection bias in studies of pubertal timing.

objectiveWe aimed to explore the risk of selection bias due to non-participation in a newly established puberty cohort.

methodsWe evaluated whether three maternal exposures chosen a priori (pre-pregnancy obesity, smoking, and alcohol drinking during pregnancy) were associated with participation, whether pubertal timing was associated with participation, and whether selection bias influenced the associations between these exposures and pubertal timing. In total, 22 439 children from the Danish National Birth Cohort born 2000-2003 were invited to the Puberty Cohort and 15 819 (70%) participated. Exposures were self-reported during pregnancy. Pubertal timing was measured using a previously validated marker, "the height difference in standard deviations" (HD:SDS), which is the difference between pubertal height and adult height, both in standard deviations. For this study, pubertal height at around 13 years in sons and around 11 years in daughters was obtained from an external database, and adult height was predicted based on parental height reported by mothers.

resultsParticipation was associated with most exposures but not with pubertal timing, measured by HD:SDS. The associations between exposures and HD:SDS were comparable for participants only and all invited for participation.

conclusionIn conclusion, the risk of selection bias in aetiologic studies on pubertal timing in the Puberty Cohort appears minimal.

Indexed as

MenarchePrenatal Exposure Delayed EffectsAdultChildCohort StudiesFemaleHumansPregnancyPubertySelection Biascohort studieslost to follow-upmenarchepubertyselection biassexual maturation

Identifiers

PMID32319135
PMCPMC7754153
OpenAlexW3016995935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.