Evidence map›Paper›PMID 32318899›Full record

ArticleCellular and molecular neurobiology2021

Response of Voltage-Gated Sodium and Calcium Channels Subtypes on Dehydroepiandrosterone Treatment in Iron-Induced Epilepsy.

Chandra Prakash, Monika Mishra, Pavan Kumar, Vikas Kumar, Deepak Sharma

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Chandra PrakashNeurobiology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India.
Monika MishraNeurobiology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India.
Pavan KumarDepartment of Developmental Neurogenetics, Medical University of South Carolina, Charleston, SC, USA.
Vikas KumarNeurobiology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India.
Deepak SharmaNeurobiology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India. sharmadeepakjnu@gmail.com.ORCID https://orcid.org/0000-0002-9929-3119
Jawaharlal Nehru University · INMedical University of South Carolina · US

Funding

Department of Biotechnology , Ministry of Science and Technology BT/PR12754/INF/122/2/2016Indian Council of Medical Research 54/1/CFP/GER/2011/NCD-II
6 · The paper itself

Abstract

Epilepsy is a neurological disorder characterized by the occurrence of spontaneous and recurrent seizures. In post-traumatic epilepsy (PTE), the mechanism of epileptogenesis is very complex and seems to be linked with voltage-gated ion channels. Dehydroepiandrosterone (DHEA), a neurosteroid have shown beneficial effect against various neurological disorders. We investigated antiepileptic effect of DHEA with respect to expression of voltage-gated ion channels subtypes in iron-induced epilepsy. Iron (FeCl

Indexed as

AnimalsCalcium ChannelsDehydroepiandrosteroneEpilepsyGlial Fibrillary Acidic ProteinHippocampusIronMaleMicrotubule-Associated ProteinsRatsRats, WistarRNA, MessengerSodium ChannelsCalcium ChannelsDehydroepiandrosteroneGlial Fibrillary Acidic ProteinIronMAP2 protein, ratMicrotubule-Associated ProteinsRNA, MessengerSodium ChannelsAntiepileptic effectDehydroepiandrosteronePost-traumatic epilepsySeizuresVGCCsVGSCs

Identifiers

PMID32318899
PMCPMC11448620
OpenAlexW3016941871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.