ArticleJournal of family medicine and primary care2020
Heart rate variability is reduced in normal pregnancy irrespective of trimester: A cross-sectional study from Gujarat, India.
Article in Journal of family medicine and primary care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Article
- Heterogeneous effects of physical activity on physiological stress during pregnancy.PLOS digital health · 2025Article
- Investigating the role of maternal heart rate variability in the onset of labor.Frontiers in medicine · 2025Article
- Heart rate variability and perinatal depressive symptoms: A scoping review protocol.Brain, behavior, & immunity - health · 2024Article
- Evaluating the Impact of an App-Delivered Mindfulness Meditation Program to Reduce Stress and Anxiety During Pregnancy: Pilot Longitudinal Study.JMIR pediatrics and parenting · 2023Article
- Monitoring one heart to help two: heart rate variability and resting heart rate using wearable technology in active women across the perinatal period.BMC pregnancy and childbirth · 2022Article
- The Utilization of Heart Rate Variability for Autonomic Nervous System Assessment in Healthy Pregnant Women: Systematic Review.JMIR bioinformatics and biotechnology · 2022Review
- Trends in Heart Rate and Heart Rate Variability During Pregnancy and the 3-Month Postpartum Period: Continuous Monitoring in a Free-living Context.JMIR mHealth and uHealth · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPregnancy is associated with profound cardiovascular adaptation with altered cardiac autonomic balance. It can be studied by heart rate variability (HRV) which indicates beat to beat RR interval variation on ECG.
objectiveWe studied 5 min HRV in normal pregnant females divided by trimesters, compared to matched control. METHODOLOGY: We recruited 89 normal pregnant females and 30 age matched controls. Five minutes resting HRV was measured by Variowin HR, software-based instrument, by standard protocols to yield time-domain, frequency domain, and Poincare plot parameters. They were further compared between groups for difference.
resultsCase groups (three based on trimesters) and control group were comparable. There was reduced HRV in case than control group, with statistical significance for all, more for frequency domain than time-domain or Poincare plot parameters. There was no pattern of HRV trend across three trimesters, but mostly second trimester was associated with major decline. Primipara revealed significantly reduced HRV than multipara, but anemia or working status was not significantly associated with HRV in case group.
conclusionThere is global HRV reduction in normal pregnancy across all trimesters, associated with primiparity. This indicates pregnancy as a significant risk with reference to altered cardiac balance and use of HRV as a good tool to assess the same.
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