Evidence map›Paper›PMID 32318257›Full record

ArticleParkinson's disease2020

Ultrasonography of the Vagus Nerve in the Diagnosis of Parkinson's Disease.

Ovidijus Laucius, Renata Balnytė, Kęstutis Petrikonis, Vaidas Matijošaitis, Neringa Jucevičiūtė, Tadas Vanagas, Vytautas Danielius

Open access · goldAbstract read
In one paragraph

Article in Parkinson's disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Correlation between right vagus nerve cross-sectional area and abnormal heart rate with deep breathing in Parkinson's disease.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
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  6. Neurophysiological and ultrasonographic comparative study of autonomous nervous system in patients suffering from fibromyalgia and generalized anxiety disorder.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ovidijus LauciusDepartment of Neurology, Lithuanian University of Health Sciences, Eivenių str. 2, LT-50009 Kaunas, Lithuania.ORCID https://orcid.org/0000-0001-8397-1715
Renata BalnytėDepartment of Neurology, Lithuanian University of Health Sciences, Eivenių str. 2, LT-50009 Kaunas, Lithuania.
Kęstutis PetrikonisDepartment of Neurology, Lithuanian University of Health Sciences, Eivenių str. 2, LT-50009 Kaunas, Lithuania.
Vaidas MatijošaitisDepartment of Neurology, Lithuanian University of Health Sciences, Eivenių str. 2, LT-50009 Kaunas, Lithuania.
Neringa JucevičiūtėFaculty of Medicine, Medical Academy, Lithuanian University of Health Sciences, Mickevičiaus str. 9, LT 44307 Kaunas, Lithuania.ORCID https://orcid.org/0000-0002-2635-6537
Tadas VanagasFaculty of Medicine, Medical Academy, Lithuanian University of Health Sciences, Mickevičiaus str. 9, LT 44307 Kaunas, Lithuania.ORCID https://orcid.org/0000-0001-9204-4534
Vytautas DanieliusFaculty of Medicine, Medical Academy, Lithuanian University of Health Sciences, Mickevičiaus str. 9, LT 44307 Kaunas, Lithuania.
Lithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is currently impossible to diagnose Parkinson's disease (PD) in the premotor phase even though at the time of motor symptom onset the number of already degenerated dopaminergic substantia nigra neurons is considerable. Degeneration of the dorsal nucleus of the vagus nerve (VN) has been reported early in the disease course, and it could lead to impaired function of the VN, resulting in certain nonmotor symptoms of PD. Therefore, we raised a hypothesis that the loss of VN neurons could result in a smaller diameter of the VN among PD patients.

methods20 PD patients and 20 age- and gender-matched individuals without any neurodegenerative disease were enrolled in a pilot study. The diameters of the right and left VNs were measured using ultrasonography, their average was calculated, and the narrower VN diameter was noted separately.

resultsNo difference was found between the PD and control groups neither in the average VN diameter (mean 1.17; 95% confidence interval (CI) 1.10-1.24 vs. 1.13; 1.07-1.18, mm;

conclusionsTo conclude, no differences were found in VN diameter between the PD and control groups. Therefore, our data do not support the hypothesis that PD could be associated with a smaller diameter of the VN.

Identifiers

PMID32318257
PMCPMC7150709
OpenAlexW3015110662

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.