Evidence map›Paper›PMID 32317953›Full record

ArticleFrontiers in human neuroscience2020

Elevated Thresholds for Light Touch in Children With Autism Reflect More Conservative Perceptual Decision-Making Rather Than a Sensory Deficit.

Jennifer M Quinde-Zlibut, Christian D Okitondo, Zachary J Williams, Amy Weitlauf, Lisa E Mash, Brynna H Heflin, Neil D Woodward, Carissa J Cascio

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Jennifer M Quinde-ZlibutGraduate Program in Neuroscience, Vanderbilt University, Nashville, TN, United States.
Christian D OkitondoGraduate Program in Biostatistics, Georgia State University, Atlanta, GA, United States.
Zachary J WilliamsGraduate Program in Neuroscience, Vanderbilt University, Nashville, TN, United States.
Amy WeitlaufDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, United States.
Lisa E MashSan Diego Joint Doctoral Program in Clinical Psychology, San Diego State University/University of California, San Diego, CA, United States.
Brynna H HeflinGraduate Program in Clinical Psychology, Florida International University, Miami, FL, United States.
Neil D WoodwardDepartment of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, United States.
Carissa J CascioFrist Center for Autism and Innovation, Vanderbilt University, Nashville, TN, United States.
Vanderbilt University Medical Center · USCenter for Autism and Related Disorders · USFlorida International University · USGeorgia State University · USJohn F. Kennedy Center for the Performing Arts · USUniversity of California, San Diego · USVanderbilt University · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARRELL, FRANK E. · 2015 to 2019
$7.1M
Medical Scientist Training ProgramT32GM152284 · NIGMS · VANDERBILT UNIVERSITY · PI Christopher S. Williams · 2024 to 2026
$4.8M
Sensorimotor integration governing facial expression production in autism.R01MH102272 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASCIO, CARISSA J · 2014 to 2023
$4.3M
Mapping Thalamocortical Networks Across Development in ASDR21MH101321 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASCIO, CARISSA J, WOODWARD, NEIL D. · 2014 to 2015
$432k
NCATS NIH HHS UL1 TR002243NICHD NIH HHS P50 HD103537NICHD NIH HHS U54 HD083211NIGMS NIH HHS T32 GM007347NIGMS NIH HHS T32 GM152284NIMH NIH HHS R01 MH102272NIMH NIH HHS R21 MH101321
6 · The paper itself

Abstract

Individuals with autism spectrum disorder (ASD) are often behaviorally hyper-reactive to light touch, but it is unclear to what degree this arises from a fundamental sensory difference vs. higher order systems for attention or emotion processing. Thus far, experimental findings for light touch detection are mixed, and few previous studies have independently considered sensitivity (the ability to discriminate signal from noise) and decision criterion (the overall response bias or tendency to answer "yes" or "no" in a detection task). We tested a large sample of children, adolescents, and adults with ASD (

Indexed as

autismpsychophysicsresponse biassignal detectiontactile

Identifiers

PMID32317953
PMCPMC7154145
OpenAlexW3016262568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.