Evidence map›Paper›PMID 32317925›Full record

ArticleFrontiers in neuroscience2020

Dopaminergic Progenitors Derived From Epiblast Stem Cells Function Similarly to Primary VM-Derived Progenitors When Transplanted Into a Parkinson's Disease Model.

Sophie V Precious, Gaynor A Smith, Andreas Heuer, Ines Jaeger, Emma L Lane, Stephen B Dunnett, Meng Li, Claire M Kelly, Anne E Rosser

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sophie V PreciousBrain Repair Group, School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Gaynor A SmithSchool of Medicine, UK Dementia Research Institute, Cardiff University, Cardiff, United Kingdom.
Andreas HeuerBrain Repair Group, School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Ines JaegerStem Cell Neurogenesis Group, School of Medicine and Biosciences, Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom.
Emma L LaneSchool of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, United Kingdom.
Stephen B DunnettBrain Repair Group, School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Meng LiStem Cell Neurogenesis Group, School of Medicine and Biosciences, Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom.
Claire M KellySchool of Health Sciences, Cardiff Metropolitan University, Cardiff, United Kingdom.
Anne E RosserBrain Repair Group, School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Cardiff University · GBCardiff Metropolitan University · GBLund University · SE

Funding

Medical Research Council MC_PC_16030/1Medical Research Council MR/L010305/1Medical Research Council MR/R022429/1
6 · The paper itself

Abstract

Neural transplantation in neurodegenerative diseases such as Parkinson's disease (PD) offers to replace cells lost during the progression of the disease process. Primary fetal ventral mesencephalon (VM), the origin of

Indexed as

dopaminergic neuronsParkinson’s diseaseprimary fetal ventral mesencephalonstem cellstransplantation

Identifiers

PMID32317925
PMCPMC7154167
OpenAlexW3013336499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.