ArticleMedical archives (Sarajevo, Bosnia and Herzegovina)2020
Evaluation of Liver Function Tests and Serum Bilirubin Levels After Laparoscopic Cholecystectomy.
Article in Medical archives (Sarajevo, Bosnia and Herzegovina), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Transient liver enzyme elevations following laparoscopic cholecystectomy: a comprehensive review.Updates in surgery · 2025Review
- Article
- Transient Elevation of Liver Function Tests and Bilirubin Levels After Laparoscopic Cholecystectomy.Medicina (Kaunas, Lithuania) · 2024Article
- Comparison of postoperative outcomes between different dissection techniques during laparoscopic cholecystectomy in rabbits: randomized study.Acta cirurgica brasileira · 2024Article
- Comparative evaluation of three laparoscopic cholecystectomy techniques in rabbit's model.Acta cirurgica brasileira · 2023Article
- The Effect of L-Hook Dissection and Scissors Dissection on Liver Injury in Laparoscopic Cholecystectomies.Cureus · 2021Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLaparoscopic cholecystectomy has been known as one of the most important prevalent and minimally invasive surgeries in medicine.
aimThe aim here was to investigate the changes in liver enzymes and bilirubin levels after laparoscopic cholecystectomy in patients diagnosed with chronic cholecystitis.
methodsThis cross-sectional study was conducted at Poursina Hospital (Rasht, Iran) and 128 patients who met both inclusion and exclusion criteria were enrolled for further investigations. After collecting the patients' bio-demographic information, levels of serum alkaline phosphatase, lactate dehydrogenase, alanine aminotransferase, aspartate aminotransferase, and bilirubin were checked before laparoscopic cholecystectomy and 24 (post-op 1) and 48 (post-op 2) h after laparoscopic cholecystectomy.
resultsNo significant difference was found in the serum levels of ALP in post-op 1 and 2 compared both to each other and to the baseline (P>0.05). Regarding AST and ALT, there was a significant increase in post-op 1 and 2 compared to their baseline values (P<0.05). However, the difference between post-op 1 and post-op 2 was not significant for these outcomes. Compared to baseline levels, LDH had a significant increase after post-op 2 (P=0.001); but not after post-op 1 (P >0.05). Moreover, total bilirubin levels showed significant increases at post-op 1 and post-op 2 from the baseline and also in comparison with each other (P < 0.05).
conclusionOur results demonstrated a transient increase in liver function tests and bilirubin after laparoscopic cholecystectomy.
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